The mental health status of ethnocultural minorities in Ontario and their mental health care
The reason for this study was to compare the pyschosocial indicators and mental health service use among diverse populations in Ontario. There was a high level of pyschosocial distress in ethnic minorities in Ontario who are not accessing mental health services.
Depression and risk of type 2 diabetes: the potential role of metabolic factors
This study looked at the interaction between depressive symptoms and metabolic dysregulations as risk factors for type II diabetes. The study found depressive symptoms and disruptions in metabolic regulation can lead to risk of type two diabetes.
Using national dietary intake data to evaluate and adapt the US Diet History Questionnaire: the stepwise tailoring of an FFQ for Canadian use
The research team evaluated the Canadian Diet History Questionnaire and adapt the US list for Canada. 4533 food and recipes were grouped into 268 food group and were measured against the different surveys. C-DHQ I and II were designed to optimize the capture of foods consumed in Canadian populationsé
A Genome-Wide Association Study to Identify Potential Germline Copy Number Variants for Sporadic Breast Cancer Susceptibility
The study wanted to determine which CNVs (copy number variations) are assoicated with sporadic BC. They also wanted to 2 distinct CNV calling algorithms to identify false positives and finally the aim of the study is identify potential candidate CNVs for follow-up replication studies.
Heart rate dependent and independent effects of beta-blockers on central hemodynamic parameters: a propensity score analysis
In this article they looked the association between beta-blocker use, heart rate, and central hemodynamics in hypertensive CARTaGENE participants. They looked at 20004 people and determined that there were unfavourable central hemodynamic profile of beta-blocker has both HR-dependent and HR-indepdent components that are similar for all frequency used beta1 selective blocker.
Clinical, Genetic, and Urinary Factors Associated with Uromodulin Excretion.
This study observed excretion of uromodulin and variations in the UMOD gene. Those with higher levels of uromodulin also had higher levels of uric acid, sodium in their bodies
G1 Gene-environment-lifestyle factors in breast cancer susceptibility: machine learning tools to build predictive models
This study hoped to build predictive models for personalized breast screening. They were able to develop good predictive models for etiologies that would cause disease, and hope their model will aid in preventing breast cancer.
Replication study of MATR3 in familial and sporadic amyotrophic lateral sclerosis
In this study, they looked at mutations of MATR3 (gene that is associated with ALS). They assessed the frequency in French Canadian populations and had a control group. They were able to determine which proteins are associated with ALS.
Comparison of the Effect of Thiazide Diuretics and Other Antihypertensive Drugs on Central Blood Pressure: Cross‐Sectional Analysis Among Nondiabetic Patients
This study used CARTaGENE data to determine to assess the noninferority of TDs relative to different classes of antihypertensive medications in relation to central blood pressure. No major differences were noted and it was shown that TDs are at least as effective as other first line medications that are available.
Neighborhood greenspace and health in a large urban center
This study focused on self-reported mental health study looked at the density of trees/green spaces in various neighbourhoods in Toronto. Those that had more trees reported that they were happier and felt better about their mental health.