Diabetes, Brain Infarcts, Cognition and Small Vessels in the Canadian Alliance for Healthy Hearts and Minds Study
The CAHHM study collected brain and carotid magnetic resonance imaging (MRI) and two cognitive tests (DSST and MoCA) in a cross-sectional sample of 7,733 men and women. It was concluded that small vessel disease characterizes much of the relationship between diabetes and vascular brain injury. However, additional factors are required to disentangle the relationship between diabetes and cognitive impairment.
The Canadian Alliance for Healthy Hearts and Minds: How well does it reflect the Canadian population?
The representativeness of the Canadian Alliance for Healthy Hearts and Minds (CAHHM-HSR) cohort was evaluated by comparing to region matched respondents of the 2015 Canadian Community Health Survey Rapid Response module (CCHS-RR). CAHHM-HSR participants were older, more often women, more likely Chinese, and had higher education, hypertension, hypercholesterolemia and cardiac testing than the general Canadian population. Despite these differences, the INTERHEART risk score was similar.
The Relationship of Sleep Duration with Ethnicity and Chronic Disease in a Canadian General Population Cohort
This study used questionnaire data from the Ontario Health Study to determine how ethnicity-specific differences in sleep duration affect health outcomes. It was found that both sleep duration and ethnicity were independent significant predictors for various morbidities such as diabetes, stroke, and depression.
Physical Activity is Associated With Reduced Prevalence of Self-Reported Obstructive Sleep Apnea in a Large, General Population Cohort Study
The researchers used Ontario Health Study data to determine if physical activity would reduce the prevalence of OSA. Upon determining the prevalence of OSA, the reseachers were able to do a cross sectional analysis to determine that increased physical activity had a statistical significance of (P ≤ 0.045). Moderate activity did not have much of an impact on the prevalence of OSA. These results showed that increased physical activity would be a preventative measure for OSA.
Reduced Cognitive Assessment Scores Among Individuals With Magnetic Resonance Imaging–Detected Vascular Brain Injury
This study investigated if scores on a cognitive screen were lower in individuals with higher cardiovascular risk, and those with covert vascular brain injury. Among a middle-aged community-dwelling population, scores on a cognitive screen were lower in individuals with higher cardiovascular risk factors or MRI vascular brain injury. Much of the population attributable risk of low cognitive scores can be attributed to lower educational attainment, higher cardiovascular risk factors, and MRI vascular brain injury.
Harmonization of the Health and Risk Factor Questionnaire data of the Canadian Partnership for Tomorrow Project: a descriptive analysis
This paper describes how data is harmonized the health and risk factor questionnare and provides an overview of information required to use the core data that has been created. The reason for the harmonization is to have a unique data set including data on health and risk factors from over 307000 Canadians.
The Canadian Partnership for Tomorrow Project: a pan-Canadian platform for research on chronic disease prevention
In order to understand the risk factors for disease, participants across the study were recruited across 5 provinces. Body samples and physical information was collected from these people. They then harmonized this data. The hope out of this paper was that the samples afford strides in research both nationally nad internationally.
The author who wasn’t there? Fairness and attribution in publications following access to population biobanks
This study conducted a document analysis that looked at publication ethics and authorship with population biobanks. In their findings, they reported a 3-step approach: 1) the biobank should be given proper acknowledgement 2) co-authorship should be encouraged to foster colloboration amongst researchers 3) referencing/citiations should be readily available
Atopic dermatitis and risk of hypertension, type 2 diabetes, myocardial infarction and stroke in a cross‐sectional analysis from the Canadian Partnership for Tomorrow Project
This study wanted to determine if there was an association with atopic dermatitis and hypertension/heart attack/stroke/type II diabetes. It was found in a cross-sectional study that AD is not really a major risk factor for cardiovascular disease.
Rationale, design, and methods for Canadian alliance for healthy hearts and minds cohort study (CAHHM) – a Pan Canadian cohort study
Canadian Alliance for Healthy Hearts and Minds (CAHHM) is a pan-Canadian, prospective, multi-ethnic cohort study being conducted in Canada. This project has sed CPTP data to help and assist it. CAHHM is a prospective cohort study which aims to examine the health of adults living in Canada.