Publications

These publications are examples of research made possible with data from CanPath and its regional cohorts.

2020

The Canadian Alliance for Healthy Hearts and Minds: How well does it reflect the Canadian population?

Authors: Ruth E. Hall, Natasa Tusevljak, C. Fangyun Wu, Quazi Ibrahim, Karleen Schulze, Anam M. Khan, Dipika Desai, Philip Awadalla, Philippe Broet, Trevor J.B. Dummer, Jason Hicks, Jean-Claude Tardif, Koon K. Teo, Jennifer Vena, Douglas Lee, Matthias Friedrich, Sonia S. Anand, Jack V. Tu

The representativeness of the Canadian Alliance for Healthy Hearts and Minds (CAHHM-HSR) cohort was evaluated by comparing to region matched respondents of the 2015 Canadian Community Health Survey Rapid Response module (CCHS-RR). CAHHM-HSR participants were older, more often women, more likely Chinese, and had higher education, hypertension, hypercholesterolemia and cardiac testing than the general Canadian population. Despite these differences, the INTERHEART risk score was similar.

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2020

Reduced Cognitive Assessment Scores Among Individuals With Magnetic Resonance Imaging–Detected Vascular Brain Injury

Authors: Sonia S. Anand, Matthias G. Friedrich, Dipika Desai, Karleen M. Schulze, Philip Awadalla, David Busseuil, Trevor J.B. Dummer, Sébastien Jacquemont, Alexander Dick, David Kelton, Anish Kirpalani, Scott A. Lear, Jonathan Leipsic, Michael D. Noseworthy, Louise Parker, Grace Parraga, Paul Poirier, Paula Robson, Jean-Claude Tardif, Koon Teo, Jennifer Vena, Salim Yusuf, Alan R. Moody, Sandra E. Black, Eric E. Smith,

This study investigated if scores on a cognitive screen were lower in individuals with higher cardiovascular risk, and those with covert vascular brain injury. Among a middle-aged community-dwelling population, scores on a cognitive screen were lower in individuals with higher cardiovascular risk factors or MRI vascular brain injury. Much of the population attributable risk of low cognitive scores can be attributed to lower educational attainment, higher cardiovascular risk factors, and MRI vascular brain injury.

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2019

Diet Quality among Cancer Survivors and Participants without Cancer: A Population-Based, Cross-Sectional Study in the Atlantic Partnership for Tomorrow’s Health Project

This study investigated the diet quality of cancer survivors relative to participants without cancer, overall and by cancer site and time from diagnosis. It found that there was considerable room for dietary improvement regardless of cancer status, highlighting the need for dietary interventions, especially among cancer survivors, who are at higher risk for secondary health problems.

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2019

Harmonization of the Health and Risk Factor Questionnaire data of the Canadian Partnership for Tomorrow Project: a descriptive analysis

Authors: Isabel Fortier, Nataliya Dragieva, Matilda Saliba, Camille Craig, Paula J. Robson

This paper describes how data is harmonized the health and risk factor questionnare and provides an overview of information required to use the core data that has been created. The reason for the harmonization is to have a unique data set including data on health and risk factors from over 307000 Canadians.

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2018

Cohort Profile: The British Columbia Generations Project (BCGP)

Authors: Anar Dhalla, Treena E McDonald, Richard P Gallagher, John J Spinelli, Angela R Brooks-Wilson, Tim K Lee, Calvin Lai, Marilyn J Borugian, Ryan R Woods, Nhu D Le, Trevor J B Dummer

29850 people in BC were surveyed between the ages of 35-69. Information such as health and lifestyle, physical measurements, biosamples, and genotyping were done.

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2018

The Canadian Partnership for Tomorrow Project: a pan-Canadian platform for research on chronic disease prevention

Authors: Trevor J.B. Dummer, Philip Awadalla, Catherine Boileau, Camille Craig, Isabel Fortier, Vivek Goel, Jason M.T. Hicks, Sébastien Jacquemont, Bartha Maria Knoppers, Nhu Le, Treena McDonald, John McLaughlin, Anne-Marie Mes-Masson, Anne-Monique Nuyt, Lyle J. Palmer, Louise Parker, Mark Purdue, Paula J. Robson, John J. Spinelli, David Thompson, Jennifer Vena, Ma’n Zawati

In order to understand the risk factors for disease, participants across the study were recruited across 5 provinces. Body samples and physical information was collected from these people. They then harmonized this data. The hope out of this paper was that the samples afford strides in research both nationally nad internationally.

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2018

Plasma-Derived Inflammatory Proteins Predict Oral Squamous Cell Carcinoma

Authors: Kelly Vi Ping Liu, Xian Jun David Lu, Yuqi Sarah Zhu, Nhu Le, Hugh Kim, Catherine Poh

This study looked at a multiplex approach to screen plasma derived biomarkers and to examine the association of proteins with throat cancer. They looked at 260 plasma samples and they screened 82 biomarkers to look for disease.

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2018

The author who wasn’t there? Fairness and attribution in publications following access to population biobanks

Authors: Erika Kleiderman, Amy Pack, Pascal Borry, Ma'n Zawati

This study conducted a document analysis that looked at publication ethics and authorship with population biobanks. In their findings, they reported a 3-step approach: 1) the biobank should be given proper acknowledgement 2) co-authorship should be encouraged to foster colloboration amongst researchers 3) referencing/citiations should be readily available

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2017

Atopic dermatitis and risk of hypertension, type 2 diabetes, myocardial infarction and stroke in a cross‐sectional analysis from the Canadian Partnership for Tomorrow Project

Authors: A.M. Drucker, A. Qureshi, T. Dummer, L. Parker, W. Li

This study wanted to determine if there was an association with atopic dermatitis and hypertension/heart attack/stroke/type II diabetes. It was found in a cross-sectional study that AD is not really a major risk factor for cardiovascular disease.

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2016

Rationale, design, and methods for Canadian alliance for healthy hearts and minds cohort study (CAHHM) – a Pan Canadian cohort study

Authors: Sonia S. Anand, Jack V. Tu, Philip Awadalla, Sandra Black, Catherine Boileau, David Busseuil, Dipika Desai, Jean-Pierre Després, Russell J. de Souza, Trevor Dummer, Sébastien Jacquemont, Bartha Knoppers, Eric Larose, Scott A. Lear, Francois Marcotte, Alan R. Moody, Louise Parker, Paul Poirier, Paula J. Robson, Eric E. Smith, John J. Spinelli, Jean-Claude Tardif, Koon K. Teo, Natasa Tusevljak, Matthias G. Friedrich

Canadian Alliance for Healthy Hearts and Minds (CAHHM) is a pan-Canadian, prospective, multi-ethnic cohort study being conducted in Canada. This project has sed CPTP data to help and assist it. CAHHM is a prospective cohort study which aims to examine the health of adults living in Canada.

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