Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
To investigate the genetics of gene expression, the team performed cis- and trans-expression quantitative trait locus (eQTL) analyses using blood-derived expression from 31,684 individuals through the eQTLGen Consortium.
Psychosocial factors and cancer incidence (PSY-CA): Protocol for individual participant data meta-analyses
This study aims (1) to test whether psychosocial factors are associated with the incidence of any cancer; (2) to test the interaction between psychosocial factors and factors related to cancer risk with regard to the incidence of cancer; and (3) to test the mediating role of health behaviors in the relationship between psychosocial factors and the incidence of cancer.
Post-Treatment Adverse Health Correlates among Prostate Cancer Survivors in a Sample of Men Residing in Atlantic Canada
A cross-sectional analysis was conducted on a subsample of 632 male participants aged 36–69 the Atlantic PATH. The primary outcomes were the presence of mild, moderate or severe depression or anxiety indicators and were assessed using the seven-item generalized anxiety disorder (GAD-7) scale and the nine-item Patient Health Questionnaire (PHQ-9), respectively.
Environmental Correlates of Physical Activity, Sedentary Behavior, and Self-Rated Health in Chronic Obstructive Pulmonary Disease
This study sought to investigate associations between the environment and physical activity, sedentary behavior, and self-rated health in Chronic Obstructive Pulmonary Disease. The new data may identify barriers to physical activity and assist clinicians in the prescription of exercise for individuals living with COPD.
Age and Sex-Specific Associations in Health Risk Factors for Chronic Disease: Evidence from the Atlantic Partnership for Tomorrow’s Health (PATH) Cohort
The objective of this study was to discern health risk factors for chronic disease by age and sex using health risk factor data from participants of the Atlantic PATH (n = 16,165). The study found evident differences in health risk factors for males and females, as well as across age groups.
Examining the etiology of early-onset breast cancer in the Canadian Partnership for Tomorrow’s Health (CanPath)
The objective of this study was to investigate relationships between modifiable and non-modifiable risk factors and early-onset breast cancer among the BC Generations Project, Alberta’s Tomorrow Project and Ontario Health Study. In this study, measures of adiposity, pregnancy history, and familial history of breast cancer are important risk factors for early-onset breast cancer.
Dietary patterns with combined and site-specific cancer incidence in Alberta’s Tomorrow Project cohort
This study used data from the Alberta’s Tomorrow Project to examine the association between dietary patterns derived with two methods, and combined and site-specific cancer incidence in Canada.
The association between mental health and shift work: Findings from the Atlantic PATH study
This study found that shift workers reported higher levels of anxiety, depression, and lower self-rated health than non-shift workers. Shift workers were more likely to report major depression and poor self-rated health, and female shift workers were more likely to report depressive symptoms and poor self-rated health.
Epidemiological characteristics of the COVID-19 spring outbreak in Quebec, Canada: a population-based study
This study examined the epidemiological and socio-economic impact of the spring 2020 outbreak of COVID-19 on the Quebec population. An online survey of the participants of CARTaGENE was conducted, with 8,129 respondents. The study found some discrepancies between the symptoms associated with being tested and being positive. The results also emphasize the need for increasing the accessibility of testing for the general population.
The effect of different methods to identify, and scenarios used to address energy intake misestimation on dietary patterns derived by cluster analysis
This study used self-reported food frequency and physical activity data from Alberta’s Tomorrow Project participants to compare the revised-Goldberg and the predicted total energy expenditure methods in their ability to identify misreporters of energy intake.