A Prospective Analysis of Plasma Phospholipid Fatty Acids and Breast Cancer Risk in 2 Provinces in Canada
This study compared participants from BCGP and ATP and examined whether there was an association between fatty acid status and the risk of breast cancer, including location, menopausal status, and waist-to-hip ratio as key variables. Findings suggest that regional variations in fatty acid status influence breast cancer risk and highlights the complexity and difficulty in using fatty acid status to predict breast cancer risk in diverse populations without the consideration of other risk factors.
Administering a combination of online dietary assessment tools, the Automated Self-Administered 24-Hour Dietary Assessment Tool and Diet History Questionnaire-II, in a cohort of adults in Alberta’s Tomorrow Project
This study determined the feasibility and acceptability of combining the ASA24-2016 and the past-year Diet History Questionnaire web-based tools in a subset of participants in the ATP cohort. The study found that combining ASA24-2016 recalls and the DHQ-II is feasible in this group of ATP participants.
Social Jetlag and Prostate Cancer Incidence in Alberta’s Tomorrow Project: A Prospective Cohort Study
Social jetlag has been linked with obesity, metabolic disorders, and cardiovascular risk in previous research. This study assessed social jetlag in 7455 cancer-free men in Alberta’s Tomorrow Project and followed them for on average 9.6 years, 250 men were diagnosed with prostate cancer. The study found that the more social jetlag men experienced, the greater their prostate cancer risk was.
The Importance of Cancer Registry Linkage for Studying Rare Cancers in Prospective Cohorts
This research study evaluated the validity of self-reported cancer diagnosis in ATP by linking to the Alberta Cancer Registry. The first instance of self-reported cancer in a follow-up survey was compared to the first cancer diagnosis in the ACR after enrollment. The study found that rare cancers were less likely to be captured by active follow-up than common cancers.
Combinations of modifiable lifestyle behaviours in relation to colorectal cancer risk in Alberta’s Tomorrow Project
The researchers sought to identify distinct clusters of individuals that exhibit unique patterns of modifiable life-style related behaviours and determine how these patterns are associated with the risk of developing colorectal cancer. The team identified 7 unique behaviours where the cancer risk was 2.34-2.87 times higher for the high-risk groups than the low-risk groups.
Diabetes, Brain Infarcts, Cognition and Small Vessels in the Canadian Alliance for Healthy Hearts and Minds Study
The CAHHM study collected brain and carotid magnetic resonance imaging (MRI) and two cognitive tests (DSST and MoCA) in a cross-sectional sample of 7,733 men and women. It was concluded that small vessel disease characterizes much of the relationship between diabetes and vascular brain injury. However, additional factors are required to disentangle the relationship between diabetes and cognitive impairment.
High-sensitivity C-reactive protein, hemoglobin A1c and breast cancer risk: a nested case–control study from Alberta’s Tomorrow Project cohort
This study examined the associations between high-sensitivity C-reactive protein (hsCRP) and hemoglobin A1c (HbA1c), common biomarkers of inflammation and insulin resistance, respectively, with breast cancer risk, while adjusting for measures of excess body size. These data suggest that hsCRP may be associated with elevated breast cancer risk, independent of excess body size. However, elevated concentrations of HbA1c did not appear to increase breast cancer risk in apparently healthy women.
Diet Quality and Health Service Utilization for Depression: A Prospective Investigation of Adults in Alberta’s Tomorrow Project
This study investigated the association of depression with diet quality by studying dietary patterns of 25,016 participants in the Alberta cohort using data from the past year food frequency questionnaire. It was found that higher quality diets were associated with a lower number of physician visits for depression.
The Canadian Alliance for Healthy Hearts and Minds: How well does it reflect the Canadian population?
The representativeness of the Canadian Alliance for Healthy Hearts and Minds (CAHHM-HSR) cohort was evaluated by comparing to region matched respondents of the 2015 Canadian Community Health Survey Rapid Response module (CCHS-RR). CAHHM-HSR participants were older, more often women, more likely Chinese, and had higher education, hypertension, hypercholesterolemia and cardiac testing than the general Canadian population. Despite these differences, the INTERHEART risk score was similar.
Co-consumption of Vegetables and Fruit, Whole Grains, and Fiber Reduces the Cancer Risk of Red and Processed Meat in a Large Prospective Cohort of Adults from Alberta’s Tomorrow Project
This study examined whether co-consumption of red and processed meat with key foods items and food constituents recommended for cancer prevention (vegetables and fruit, whole grains, and fiber) mitigates cancer incidence.