The National Cancer Institute Cohort Consortium: An International Pooling Collaboration of 58 Cohorts from 20 Countries
The NCI Cohort Consortium was founded in 2001 and brings together 58 cancer epidemiology cohorts from 20 countries to undertake large-scale pooling research. This article outlines the structure, governance, methods of working, and the participating cohorts (including CanPath), publications and activities of the consortium.
Metabolic profiling of adherence to diet, physical activity and body size recommendations for cancer prevention
This study examined cross-sectional associations between metabolites and cancer preventive behaviors as well as the relevance to cancer-related pathways among 120 participants with no history of smoking or cancer. Cancer preventive behaviors were associated with complex metabolic signatures, including alterations in pathways known to be involved in cancer pathogenesis.
Fruit and vegetable intake and body adiposity among populations in Eastern Canada: the Atlantic Partnership for Tomorrow’s Health Study
This was a cross-sectional study that looked at 26340 individuals (7979 men/18361 women). They looked at data on fruits/vegetable intake, sociodemographic and behavioural factors. The consumption of fruits and vegetables was inversely associated with higher body fat in these populations.
Cohort Profile: The British Columbia Generations Project (BCGP)
29850 people in BC were surveyed between the ages of 35-69. Information such as health and lifestyle, physical measurements, biosamples, and genotyping were done.
Physical Activity and Cancer Incidence in Alberta’s Tomorrow Project: Results from a Prospective Cohort of 26,538 Participants.
They were able to determine that a moderate to high level of physical activity could lead to a modest protection against the development of all cancer.
Differences in adiposity and diet quality among individuals with inflammatory bowel disease in Eastern Canada
This study looked at the relationship between diet quality and body composition in participants with IBD. There was a positive correlation between adiposity and those who ate processed grains, excess meats; there was a negative correlation between those who consumed lots of fruits/vegetables, whole grains. There was distinct difference in adiposity and diet quality were observed in individuals
The Canadian Partnership for Tomorrow Project: a pan-Canadian platform for research on chronic disease prevention
In order to understand the risk factors for disease, participants across the study were recruited across 5 provinces. Body samples and physical information was collected from these people. They then harmonized this data. The hope out of this paper was that the samples afford strides in research both nationally nad internationally.
Gene-by-environment interactions in urban populations modulate risk phenotypes
From ∼1000 individuals of a founder population in Quebec, we reveal a substantial impact of the environment on the transcriptome and clinical endophenotypes, overpowering that of genetic ancestry. Air pollution impacts gene expression and pathways affecting cardio-metabolic and respiratory traits, when controlling for genetic ancestry.
Development of an on-line interactive map to display environmental health assessments of Canadian communities: knowledge-translation to support collaborations for health
This report describes an on-line interactive map developed by the Canadian Alliance for Healthy Hearts and Minds. It contains information from over 2,000 communities across Canada!
Plasma-Derived Inflammatory Proteins Predict Oral Squamous Cell Carcinoma
This study looked at a multiplex approach to screen plasma derived biomarkers and to examine the association of proteins with throat cancer. They looked at 260 plasma samples and they screened 82 biomarkers to look for disease.