Impact of adherence to cancer-specific prevention recommendations on subsequent risk of cancer in participants in Alberta’s Tomorrow Project.
This study wanted to see if cancer-specific recommendations actually prevented cancer. They found that those who adhered to said recommendations saw lower risk of develop cancer over time.
Fracture status in middle-aged individuals with early CKD: cross-sectional analysis of the CARTaGENE survey
In this cross-sectional analysis, the study team determined that CKD was not correlated with increase fractures, was not a modification factor between calcaneal QUS and fracture, but modified the association between clinical, pharmacological parameters and fracture.
Nuclear genetic regulation of the human mitochondrial transcriptome
They analyzed more than 11000 RNA sequencing libraries across 36 tissue/cell types and they found considerable variation in mitochondrial gene expression along the transcriptome. This was also looked at tissues and inviduals and highlighted the importance of cell-type specific and post transcriptional processes in shaping mitochondrial-encoded RNA levels.
Central body fatness is a stronger predictor of cancer risk than overall body size
They wanted to see the relationship between body size and weight distribution for cancer risk. They had a sample size of 26607 and determined that men have a 33% increased risk of cancer, while women have 22% increased risk. Essentially central adiposity appears to be a strong predictor of all-cancer risk than actual body size.
Strategies to Address Misestimation of Energy Intake Based on Self-Report Dietary Consumption in Examining Associations Between Dietary Patterns and Cancer Risk
The objective of this study was to determine the influence of strategies of handling misestimation of energy intake (EI) on observed associations between dietary patterns and cancer risk.
Sleep and cancer incidence in Alberta’s Tomorrow Project cohort
This article looked at the relationship between cancer incidence and sleeping patterns. They found there was a correlation between sleep duration and cancer etiology
Identifying Rheumatoid Arthritis Cases within the Quebec Health Administrative Database
The team’s objective was to calculate rheumatoid arthritis point prevalence in the CARTaGENE cohort. They also aimed to estimate sensitivity/specificity. In the study, they were looking at 3 factors: number of years of billing data, addition of self reported information of RA diagnosis and drugs, and adjustment for calculation error. They found that there was a RAMQ sensitivity of 84% and specificity of 99.8%. Their results showed variations in the prevalence point estimates of the 3 factors being assessed.
Green space associations with mental health and cognitive function
This study was done so that they could determine the relationship between mental health and access to green space. They enrolled 8144 people and used questionnares to measure any depression/anxiety. They found that while urban green space affords a lower depression score, it does not affect cognitive function.
Uromodulin in a Pathway Between Decreased Renal Urate Excretion and Albuminuria
The study team evaluated the impact of candidate variants in the main urate transporter genes, and also they examined the urumodulin/sodium excretion as mediators of the association between FEUA and uACR. Out of the 737 participants, 593 were observed in the final analysis. They found that there was an association between albuminuria with decreased renal urate excretion may be modified by the transporter SLC2A9.
Environmental health assessment of communities across Canada: contextual factors study of the Canadian Alliance for Healthy Hearts and Minds
This study aimed to report national-level community characteristics and any interprovincial, urban/rural, and Cartesian coordinate differences. Researchers developed an on-line map for public use, showing differences in fruit and vegetable availability, advertising for sweet drinks, junk food, and tobacco products, and cigarette and alcohol prices.