Publications

These publications are examples of research made possible with data from CanPath and its regional cohorts.

2019

Green space associations with mental health and cognitive function

Authors: Perry Hystad, Yves Payette, Nolwenn Noisel, Catherine Bolieau

This study was done so that they could determine the relationship between mental health and access to green space. They enrolled 8144 people and used questionnares to measure any depression/anxiety. They found that while urban green space affords a lower depression score, it does not affect cognitive function.

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2018

Uromodulin in a Pathway Between Decreased Renal Urate Excretion and Albuminuria

Authors: Alena Krajcoviechova, Francois-Christophe Marois-Blanchet, Stephan Troyanov, Francois Harvey, Pierre Dumas, Johanne Tremblay, Renata Ciftova, Philip Awadalla, Francois Madore, Pavel Hamet

The study team evaluated the impact of candidate variants in the main urate transporter genes, and also they examined the urumodulin/sodium excretion as mediators of the association between FEUA and uACR. Out of the 737 participants, 593 were observed in the final analysis. They found that there was an association between albuminuria with decreased renal urate excretion may be modified by the transporter SLC2A9.

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2018

Environmental health assessment of communities across Canada: contextual factors study of the Canadian Alliance for Healthy Hearts and Minds

Authors: ‪Russell Jude de Souza, Lise Gauvin, Natalie Williams, Scott Lear, A. P. Oliveira, Dipika Desai, Daniel Corsi, SV Subramanian, Ayesha Rana, Rishi Arora, Gillian Booth, Fahad Razak, Jeff Brook, Jack Tu, Sonia S. Anand

This study aimed to report national-level community characteristics and any interprovincial, urban/rural, and Cartesian coordinate differences. Researchers developed an on-line map for public use, showing differences in fruit and vegetable availability, advertising for sweet drinks, junk food, and tobacco products, and cigarette and alcohol prices.

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2018

The National Cancer Institute Cohort Consortium: An International Pooling Collaboration of 58 Cohorts from 20 Countries

Authors: Anthony Swerdlow, Chinonye Harvey, Roger Milne, Camille Pottinger, Celine Vachon, Lynne Wilkenes, Susan Gapstur, Mattias Johansson, Elisabete Weiderpass, Deborah Winn

The NCI Cohort Consortium was founded in 2001 and brings together 58 cancer epidemiology cohorts from 20 countries to undertake large-scale pooling research. This article outlines the structure, governance, methods of working, and the participating cohorts (including CanPath), publications and activities of the consortium.

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2018

Metabolic profiling of adherence to diet, physical activity and body size recommendations for cancer prevention

Authors: Qianqian Gu, John Spinelli, Trevor Dummer, Treena McDonald, Steven Moore, Rachel Murphy

This study examined cross-sectional associations between metabolites and cancer preventive behaviors as well as the relevance to cancer-related pathways among 120 participants with no history of smoking or cancer. Cancer preventive behaviors were associated with complex metabolic signatures, including alterations in pathways known to be involved in cancer pathogenesis.

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2018

Fruit and vegetable intake and body adiposity among populations in Eastern Canada: the Atlantic Partnership for Tomorrow’s Health Study

Authors: Vanessa DeClerq, Yunsong Cui, Trevor Dummer, Cynthia Forbes, Scott Grandy,Melanie Keats, Louise Parker, Ellen Sweeney, Zhijie Michael Yu

This was a cross-sectional study that looked at 26340 individuals (7979 men/18361 women). They looked at data on fruits/vegetable intake, sociodemographic and behavioural factors. The consumption of fruits and vegetables was inversely associated with higher body fat in these populations.

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2018

Cohort Profile: The British Columbia Generations Project (BCGP)

Authors: Anar Dhalla, Treena E McDonald, Richard P Gallagher, John J Spinelli, Angela R Brooks-Wilson, Tim K Lee, Calvin Lai, Marilyn J Borugian, Ryan R Woods, Nhu D Le, Trevor J B Dummer

29850 people in BC were surveyed between the ages of 35-69. Information such as health and lifestyle, physical measurements, biosamples, and genotyping were done.

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2018

Physical Activity and Cancer Incidence in Alberta’s Tomorrow Project: Results from a Prospective Cohort of 26,538 Participants.

Authors: AM Barberio, CM Friedenreich, BM Lynch, KL Campbell, P Arora, DR Brenner

They were able to determine that a moderate to high level of physical activity could lead to a modest protection against the development of all cancer.

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2018

Differences in adiposity and diet quality among individuals with inflammatory bowel disease in Eastern Canada

Authors: Vanessa DeClerq, Morgan Langille, Johan van Limbergen

This study looked at the relationship between diet quality and body composition in participants with IBD. There was a positive correlation between adiposity and those who ate processed grains, excess meats; there was a negative correlation between those who consumed lots of fruits/vegetables, whole grains. There was distinct difference in adiposity and diet quality were observed in individuals

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2018

The Canadian Partnership for Tomorrow Project: a pan-Canadian platform for research on chronic disease prevention

Authors: Trevor J.B. Dummer, Philip Awadalla, Catherine Boileau, Camille Craig, Isabel Fortier, Vivek Goel, Jason M.T. Hicks, Sébastien Jacquemont, Bartha Maria Knoppers, Nhu Le, Treena McDonald, John McLaughlin, Anne-Marie Mes-Masson, Anne-Monique Nuyt, Lyle J. Palmer, Louise Parker, Mark Purdue, Paula J. Robson, John J. Spinelli, David Thompson, Jennifer Vena, Ma’n Zawati

In order to understand the risk factors for disease, participants across the study were recruited across 5 provinces. Body samples and physical information was collected from these people. They then harmonized this data. The hope out of this paper was that the samples afford strides in research both nationally nad internationally.

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