Publications

These publications are examples of research made possible with data from CanPath and its regional cohorts.

2019

Strategies to Address Misestimation of Energy Intake Based on Self-Report Dietary Consumption in Examining Associations Between Dietary Patterns and Cancer Risk

Authors: Nathan Solbak, Ala Al Rajabi, Alianu Akawung, Geraldine Siou, Sharon Kirkpatrick, Paula Robson

The objective of this study was to determine the influence of strategies of handling misestimation of energy intake (EI) on observed associations between dietary patterns and cancer risk.

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2019

Sleep and cancer incidence in Alberta’s Tomorrow Project cohort

Authors: Jessica McNeil, Amanda Barberio, Christine Fredenreich, Darren Brenner

This article looked at the relationship between cancer incidence and sleeping patterns. They found there was a correlation between sleep duration and cancer etiology

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2019

Identifying Rheumatoid Arthritis Cases within the Quebec Health Administrative Database

Authors: Zeinab Slim, Cristiano Moura, Sasha Bernatsky, Elham Rahme

The team’s objective was to calculate rheumatoid arthritis point prevalence in the CARTaGENE cohort. They also aimed to estimate sensitivity/specificity. In the study, they were looking at 3 factors: number of years of billing data, addition of self reported information of RA diagnosis and drugs, and adjustment for calculation error. They found that there was a RAMQ sensitivity of 84% and specificity of 99.8%. Their results showed variations in the prevalence point estimates of the 3 factors being assessed.

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2019

Green space associations with mental health and cognitive function

Authors: Perry Hystad, Yves Payette, Nolwenn Noisel, Catherine Bolieau

This study was done so that they could determine the relationship between mental health and access to green space. They enrolled 8144 people and used questionnares to measure any depression/anxiety. They found that while urban green space affords a lower depression score, it does not affect cognitive function.

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2018

Uromodulin in a Pathway Between Decreased Renal Urate Excretion and Albuminuria

Authors: Alena Krajcoviechova, Francois-Christophe Marois-Blanchet, Stephan Troyanov, Francois Harvey, Pierre Dumas, Johanne Tremblay, Renata Ciftova, Philip Awadalla, Francois Madore, Pavel Hamet

The study team evaluated the impact of candidate variants in the main urate transporter genes, and also they examined the urumodulin/sodium excretion as mediators of the association between FEUA and uACR. Out of the 737 participants, 593 were observed in the final analysis. They found that there was an association between albuminuria with decreased renal urate excretion may be modified by the transporter SLC2A9.

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2018

Environmental health assessment of communities across Canada: contextual factors study of the Canadian Alliance for Healthy Hearts and Minds

Authors: ‪Russell Jude de Souza, Lise Gauvin, Natalie Williams, Scott Lear, A. P. Oliveira, Dipika Desai, Daniel Corsi, SV Subramanian, Ayesha Rana, Rishi Arora, Gillian Booth, Fahad Razak, Jeff Brook, Jack Tu, Sonia S. Anand

This study aimed to report national-level community characteristics and any interprovincial, urban/rural, and Cartesian coordinate differences. Researchers developed an on-line map for public use, showing differences in fruit and vegetable availability, advertising for sweet drinks, junk food, and tobacco products, and cigarette and alcohol prices.

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2018

The National Cancer Institute Cohort Consortium: An International Pooling Collaboration of 58 Cohorts from 20 Countries

Authors: Anthony Swerdlow, Chinonye Harvey, Roger Milne, Camille Pottinger, Celine Vachon, Lynne Wilkenes, Susan Gapstur, Mattias Johansson, Elisabete Weiderpass, Deborah Winn

The NCI Cohort Consortium was founded in 2001 and brings together 58 cancer epidemiology cohorts from 20 countries to undertake large-scale pooling research. This article outlines the structure, governance, methods of working, and the participating cohorts (including CanPath), publications and activities of the consortium.

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2018

Metabolic profiling of adherence to diet, physical activity and body size recommendations for cancer prevention

Authors: Qianqian Gu, John Spinelli, Trevor Dummer, Treena McDonald, Steven Moore, Rachel Murphy

This study examined cross-sectional associations between metabolites and cancer preventive behaviors as well as the relevance to cancer-related pathways among 120 participants with no history of smoking or cancer. Cancer preventive behaviors were associated with complex metabolic signatures, including alterations in pathways known to be involved in cancer pathogenesis.

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2018

Fruit and vegetable intake and body adiposity among populations in Eastern Canada: the Atlantic Partnership for Tomorrow’s Health Study

Authors: Vanessa DeClerq, Yunsong Cui, Trevor Dummer, Cynthia Forbes, Scott Grandy,Melanie Keats, Louise Parker, Ellen Sweeney, Zhijie Michael Yu

This was a cross-sectional study that looked at 26340 individuals (7979 men/18361 women). They looked at data on fruits/vegetable intake, sociodemographic and behavioural factors. The consumption of fruits and vegetables was inversely associated with higher body fat in these populations.

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2018

Cohort Profile: The British Columbia Generations Project (BCGP)

Authors: Anar Dhalla, Treena E McDonald, Richard P Gallagher, John J Spinelli, Angela R Brooks-Wilson, Tim K Lee, Calvin Lai, Marilyn J Borugian, Ryan R Woods, Nhu D Le, Trevor J B Dummer

29850 people in BC were surveyed between the ages of 35-69. Information such as health and lifestyle, physical measurements, biosamples, and genotyping were done.

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