Publications

These publications are examples of research made possible with data from CanPath and its regional cohorts.

2017

Alcohol consumption and low-risk drinking guidelines among adults: a cross-sectional analysis from Alberta’s Tomorrow Project

Authors: Darren Brenner, Tiffany Haig, Abbey Poirier, Alianu Akawung, Christine Friedenreich, Paula Robson

This article sought to determine how alcohol consumption affects the health of Alberta cohort participants and how it would be related to cancer prevention. They collected data from 26842 participants who self-reported. About 14% of men and 12% of women were over the recommened alcohol intake.Volume of consumption was positvely associated with current tobacco use in men and women. Many people drink despite the health risks, and lower drinking may reduce risks .

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2017

Adiposity Measures and Plasma Adipokines in Females with Rheumatoid and Osteoarthritis

Authors: Vanessa DeClerq, Yunsong Cui, Trevor Dummer, Cynthia Forbes, Scott Grandy,Melanie Keats, Louise Parker, Ellen Sweeney, Zhijie Michael Yu

The objective was for the researchers to see the relationship between adipokines and adiposity in individuals with rheumatoid/osteoarthritis. There were no statistical differences between levels of plasma adipokines; adiponectin levels were 6.6, 7.9, and 8.2 μg/ml, leptin levels were 10.3, 13.7, and 11.5 ng/ml, and resistin levels were 10.0, 12.1, and 10.8 ng/ml in participants without arthritis, with rheumatoid arthritis, and with osteoarthritis, respectively.

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2017

Community Engagement in Genetic Research: Results of the First Public Consultation for the Quebec CARTaGENE Project

Authors: B. Godard, J. Marshall, C. Laberge,

This article showed how beneficial CARTaGENE’s data would be, but with the caveat that the confidentiality of the participants must be acknowledged and taken into account.

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2017

Cancer incidence attributable to insufficient fibre consumption in Alberta in 2012

Authors: Anne Grundy, Abbey Poirier, Farah Khandwala, Alison McFadden, Christine M. Friedenreich, Darren R. Brenner

This study examined the effects of insufficent fibre intake in the study population. The reason for this study was that they wanted to see if there was an attributable risk with colon cancer due to lack of fibre. The study showed that 66-67% of men and 73-78% of women did not have enough fibre in their diets. As such, the attributable risk was 6.3-6.8% for men and 5.0-5.5% for women. It was found that an increase of fibre intake could reduce risks of cancer in Alberta populations.

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2016

Cohort Profile: Alberta’s Tomorrow Project 

Authors: Ming Ye, Paula Robson, Dean Eurich, Jennifer Vena, Jian-Yi Xu, Jefferey A Johnson

This article outlined the rationale as to why the it was necessary to set up a large cohort in Alberta and it aruged its feasiblity in the CPTP project. They argued that the project has many strengths and the research that came out of it but also said that it has had some problems with its recruting phase. Finally the article outlined how the data can be obtained, and discussed its funding.

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2016

Cancer incidence attributable to red and processed meat consumption in Alberta in 2012

Authors: Anne Grundy, Abbey Poirier, Farah Khandwala, Alison McFadden, Christine M. Friedenreich, Darren R. Brenner

The researchers wanted to find out what the risks of consuming red meat and processed meat. For men who ate red meat, the attributable risk was 13.6-17.9% than women which was 1.6-2.1%. The attrituable risk for men eating processed meats was also higher (3.2-4.8%) than in women. Eating red and processed meates are attrituable to 12% of colorectal cancers in AB¸.

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2016

Cancer incidence attributable to the use of oral contraceptives and hormone therapy in Alberta in 2012

Authors: Xin Grevers, Anne Grundy, Abbey E. Poirier, Farah Khandwala, Matthew Feldman, Christine M. Friedenreich, Darren R. Brenner

They wanted to esitmate the number of total cancers that were attributible to oral contraceptives. Relative risk and population attributable risk were taken from the literature, and it was found that 6.3% of cancers in Alberta were attributable to use of oral contraceptives. They found that the use of hormone therapy could increase cancer in the province and they warned that care should be taken before undergoing hormone therapy.

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2016

Cardiovascular disease and physical activity in adult cancer survivors: a nested, retrospective study from the Atlantic PATH cohort

Authors: Melanie Keats, Yunsong Cui, Scott Grandy, Louise Parker

This study looked at the correlation between cardiovasular disease and physical activity levels in cancer survivors. They assessed 1526 cancer survivors and 6034 control people. It was found the cancer survivors were 30% more likely to have a cardiovascular disease event and that cancer survivors were much less likely to participate in physical activity.

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2016

Cancer incidence attributable to tobacco in Alberta, Canada, in 2012

Authors: Abbey Poirier, Anne Grundy, Farah Khandwala, Sierra Tamminen, Darren Brenner

The 2012 study looked at number of site-specific cancers in Alberta that are attributable to tobacco exposure. They looked at data from the Canadian Community Health Survey between 2000-2007, which estimated prevalence of active/passive smoking. They found overall 37% pf tobacco related cancers were attributed to active tobacco smoking in 2012.

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2016

Association between Physical Activity and Health-Related Quality of Life in Adults with Type 2 Diabetes

Authors: Danielle Thiel, Fatima Al Sayah, Jeff Vallance, Steven Johnson, Jefferey Johnson

They wanted to determine the association between those who met physical activity and health-related quality of life in adults with type II diabetes. The mean age of the study group was about 65, and 45% of participants were female. It was found that the majority of the sample size did not meet guidelines for physical activity.

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