These publications are examples of research made possible with data from CanPath and its regional cohorts.


Combinations of modifiable lifestyle behaviours in relation to colorectal cancer risk in Alberta’s Tomorrow Project

Authors: Dylan E. O’Sullivan, Amy Metcalfe, Troy W. R. Hillier, Will D. King, Sangmin Lee, Joy Pader, Darren R. Brenner

The researchers sought to identify distinct clusters of individuals that exhibit unique patterns of modifiable life-style related behaviours and determine how these patterns are associated with the risk of developing colorectal cancer. The team identified 7 unique behaviours where the cancer risk was 2.34-2.87 times higher for the high-risk groups than the low-risk groups.

Read Publication

Comparison of the Effect of Thiazide Diuretics and Other Antihypertensive Drugs on Central Blood Pressure: Cross‐Sectional Analysis Among Nondiabetic Patients

Authors: Cristiano S. Moura, Stella S. Daskalopoulou, Linda E. Levesque, Sasha Bernatsky, Michal Abrahamowicz, Meytal A. Tsadok, Shadi Rajabi, Louise Pilote

This study used CARTaGENE data to determine to assess the noninferority of TDs relative to different classes of antihypertensive medications in relation to central blood pressure. No major differences were noted and it was shown that TDs are at least as effective as other first line medications that are available.

Read Publication

Factors related to use of prostate cancer screening: the Alberta Tomorrow Project

Authors: Harriet Richardson, Kristan Aronson, Alison James, Elizabeth McGregor, Heather Bryant

They wanted to determine the factors with PSA (prostate-specific antigen) in asymptomatic men >50. The study looked at 11000 participants and found 50% of the study group received one or more tests in their lifetime. 58% of those were asymptomatic at the time they took their last test. The study concluded that more men are getting the PSA test which showed that there are other factors other than symptoms that influence people to get tested.

Read Publication