Publications

These publications are examples of research made possible with data from CanPath and its regional cohorts.

2019

Cardiovascular risk scoring and magnetic resonance imaging detected subclinical cerebrovascular disease

Authors: Sonia S Anand, Jack V Tu, Dipika Desai, Phillip Awadalla, Paula Robson, Sébastien Jacquemont, Trevor Dummer, Nhu Le, Louise Parker, Paul Poirier, Koon Teo, Scott A Lear, Salim Yusuf, Jean-Claude Tardif, Francois Marcotte, David Busseuil, Jean-Pierre Després, Sandra E Black, Anish Kirpalani, Grace Parraga, Michael D Noseworthy, Alexander Dick, Jonathan Leipsic, David Kelton, Jennifer Vena, Melissa Thomas, Karleen M Schulze, Eric Larose, Alan R Moody, Eric E Smith, Matthias G Friedrich on behalf of the Canadian Alliance for Healthy Hearts and Minds Cohort

This study aimed to determine if simple cardiac risk scores are associated with certain MRI-deected subclinical cerebrovascular diseases. They found that the risk scores are significantly related with carotid wall volume, carotid intraplaque haemorrhage, and silent brain infarction amongst adults without known clinical cardiovascular disease.

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2019

The individual and combined effects of alcohol consumption and cigarette smoking on site-specific cancer risk in a prospective cohort of 26,607 adults: results from Alberta’s Tomorrow Project.

Authors: B Viner, AM Barberio, TR Haig, CM Fredenreich, D Brenner

This study examined the invidual and synergistic effects of modifiable lifestyle factors on overall cancer risks. The conclusions of this study were that while alcohol did not really cause a cancer risk, smoking was definitley attributed to be a factor wherein females were more affected. Those who smoked and drank were at a higher risk of developing colon/prostate cancers.

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2019

A methodologic framework to evaluate the number of cancers attributable to lifestyle and environment in Alberta

Authors: Anne Grundy, Christine M. Friedenreich, Abbey E. Poirier, Farah Khandwala, Darren R. Brenner

The team wanted to devise a way estimate the number of incident cancers that could be attributed to factors that can be varied or modified in someone`s life. They looked at 24 cancer risk factors and used estimates to quantify an exposure. By having this data, they can figure out ways to modify lifestyle and lower risk of cancer incidence.

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2019

Anthropometric changes and risk of diabetes: are there sex differences? A longitudinal study of Alberta’s Tomorrow Project

Authors: Ming Ye, Paula Robson, Dean Eurich, Jennifer Vena, Jian-Yi Xu, Jefferey A Johnson

The objective this was study was see if there was an association with antropometric change and risk of diabetes. There was a positive association between anthropometric changes and risk of diabetes was found more in men than women.

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2019

Diet quality and risk factors for cardiovascular disease among South Asians in Alberta.

Authors: CB Chan FB Subhan

A retrospective analysis of data collected from 140 South Asian adults participating in the Alberta’s Tomorrow Project was conducted. Dietary intake was assessed using a questionnaire and the Healthy Eating Index (HEI) was used an indicator of overall diet quality and adherence to dietary recommendations made by Health Canada. Central obesity (70%), hypercholesterolemia (27%), and hypertension (14%) were predominant health conditions observed in the study participants.

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2019

Harmonization of the Health and Risk Factor Questionnaire data of the Canadian Partnership for Tomorrow Project: a descriptive analysis

Authors: Isabel Fortier, Nataliya Dragieva, Matilda Saliba, Camille Craig, Paula J. Robson

This paper describes how data is harmonized the health and risk factor questionnare and provides an overview of information required to use the core data that has been created. The reason for the harmonization is to have a unique data set including data on health and risk factors from over 307000 Canadians.

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2019

Impact of adherence to cancer-specific prevention recommendations on subsequent risk of cancer in participants in Alberta’s Tomorrow Project.

Authors: JY Xu, JE Vena, HK Whelan, PJ Robson

This study wanted to see if cancer-specific recommendations actually prevented cancer. They found that those who adhered to said recommendations saw lower risk of develop cancer over time.

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2019

Central body fatness is a stronger predictor of cancer risk than overall body size

Authors: Amanda Barberio, Asalah Alareeki, Benjamin Viner, Joy Pader, Jennifer Vena, Paul Arora, Christine Fredenreich, Darren Brenner

They wanted to see the relationship between body size and weight distribution for cancer risk. They had a sample size of 26607 and determined that men have a 33% increased risk of cancer, while women have 22% increased risk. Essentially central adiposity appears to be a strong predictor of all-cancer risk than actual body size.

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2019

Strategies to Address Misestimation of Energy Intake Based on Self-Report Dietary Consumption in Examining Associations Between Dietary Patterns and Cancer Risk

Authors: Nathan Solbak, Ala Al Rajabi, Alianu Akawung, Geraldine Siou, Sharon Kirkpatrick, Paula Robson

The objective of this study was to determine the influence of strategies of handling misestimation of energy intake (EI) on observed associations between dietary patterns and cancer risk.

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2019

Sleep and cancer incidence in Alberta’s Tomorrow Project cohort

Authors: Jessica McNeil, Amanda Barberio, Christine Fredenreich, Darren Brenner

This article looked at the relationship between cancer incidence and sleeping patterns. They found there was a correlation between sleep duration and cancer etiology

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