Publications

These publications are examples of research made possible with data from CanPath and its regional cohorts.

2017

Inherited Chromosomally Integrated Human Herpesvirus 6 and Breast Cancer

Authors: Annie Gravel, Isabelle Dubuc, Angela Brooks-Wilson, Kristan Aronson, Jacques Simard, Hector Velasquez-Garcia, John Spinelli, Louis Flamand

There is a condition that affects 1% of the population where iciHHV-6 and they wanted to do know if such a mutation predisposes a person to cancer development. They found there was no statistically significant association between HHV-6 and breast cancer in women.

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2017

Deep genealogical analysis of a large cohort of participants in the CARTaGENE project (Quebec, Canada)

Authors: Marc Tremblay & Gabrielle Rouleau

The main objective of this study was to reconstruct, analyse, and compare ascending genologies of participants to CARTaGENE. They found 5110 genealogies were from four Quebec regions were constructed. They were able to find ancestry going back to the 17th century.

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2017

Self-Report Dietary Assessment Tools Used in Canadian Research: A Scoping Review

Authors: Sharon I Kirkpatrick, Lana Vanderlee, Amanda Raffoul, Jackie Stapleton, Ilona Csizmadi, Beatrice A Boucher, Isabelle Massarelli, Isabelle Rondeau, Paula J Robson

This study did a scoping review of the literature using several search engines. They looked at different food frequencies and 24 recalls. Dietary was a big measurement of this study and they said that ways to improve the application of current evidence on best practices in dietary assessment have the potential to support a stronger literature for diet and health.

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2017

The Comparative Reliability and Feasibility of the Past-Year Canadian Diet History Questionnaire II: Comparison of the Paper and Web

Authors: Geraldine Lo Siou, Ilona Cszimadi, Beatrice Boucher, Alianu Akawung, Heather Whelan, Michelle Sharma, Ala Al Rajabi, Jennifer Vena, Sharon Kirkpatrick, Anita Koushik, Isabelle Massarelli, Isabelle Rondreau, Paula Robson

This study looked at evaluating the intra-and inter-version reliability, feasability, and accetability of the Canadian Diet History Questionnaire II in a sub-sample of 648 adults. They were assigned either web or paper, 59% preferred the web version.

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2017

Lessons from Studies to Evaluate an Online 24-Hour Recall for Use with Children and Adults in Canada

Authors: Sharon Kirkpatrick, Anne Gilsing, Erin Hobbin, Nathan Solbak, Angela Wallace, Jess Haines, Alexandra Mayhew, Sarah Orr, Parminder Raina, Paula Robson, Jocelyn Sacco, Heather Whelan

This team looked at the Automated Self-Administered 24-h assessment tool and looked at 5 studies that looked at feasibility and accessibility There was a high acceptance of ADA24 in diverse samples but it was not always intuitive for everyone (kids and older adults).

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2017

Alberta’s Tomorrow Project: adherence to cancer prevention recommendations pertaining to diet, physical activity and body size

Authors: Heather Whelan, Jian-Yi Xu, Sanaz Vaseghi, Geraldine Lo Siou

This article explored a cross sectional adherence to preventing cancer. They were scored on a scale of 0-7, 0 being the least and 7 being the most. 14% of the people had scores of 5 or more, and 60% had scores of 3 or less. This means that adherence to cancer prevention is quite low in this study.

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2017

Alcohol consumption and low-risk drinking guidelines among adults: a cross-sectional analysis from Alberta’s Tomorrow Project

Authors: Darren Brenner, Tiffany Haig, Abbey Poirier, Alianu Akawung, Christine Friedenreich, Paula Robson

This article sought to determine how alcohol consumption affects the health of Alberta cohort participants and how it would be related to cancer prevention. They collected data from 26842 participants who self-reported. About 14% of men and 12% of women were over the recommened alcohol intake.Volume of consumption was positvely associated with current tobacco use in men and women. Many people drink despite the health risks, and lower drinking may reduce risks .

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2017

Adiposity Measures and Plasma Adipokines in Females with Rheumatoid and Osteoarthritis

Authors: Vanessa DeClerq, Yunsong Cui, Trevor Dummer, Cynthia Forbes, Scott Grandy,Melanie Keats, Louise Parker, Ellen Sweeney, Zhijie Michael Yu

The objective was for the researchers to see the relationship between adipokines and adiposity in individuals with rheumatoid/osteoarthritis. There were no statistical differences between levels of plasma adipokines; adiponectin levels were 6.6, 7.9, and 8.2 μg/ml, leptin levels were 10.3, 13.7, and 11.5 ng/ml, and resistin levels were 10.0, 12.1, and 10.8 ng/ml in participants without arthritis, with rheumatoid arthritis, and with osteoarthritis, respectively.

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2017

Community Engagement in Genetic Research: Results of the First Public Consultation for the Quebec CARTaGENE Project

Authors: B. Godard, J. Marshall, C. Laberge,

This article showed how beneficial CARTaGENE’s data would be, but with the caveat that the confidentiality of the participants must be acknowledged and taken into account.

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2017

Cancer incidence attributable to insufficient fibre consumption in Alberta in 2012

Authors: Anne Grundy, Abbey Poirier, Farah Khandwala, Alison McFadden, Christine M. Friedenreich, Darren R. Brenner

This study examined the effects of insufficent fibre intake in the study population. The reason for this study was that they wanted to see if there was an attributable risk with colon cancer due to lack of fibre. The study showed that 66-67% of men and 73-78% of women did not have enough fibre in their diets. As such, the attributable risk was 6.3-6.8% for men and 5.0-5.5% for women. It was found that an increase of fibre intake could reduce risks of cancer in Alberta populations.

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