Publications

These publications are examples of research made possible with data from CanPath and its regional cohorts.

2016

Cancer incidence attributable to red and processed meat consumption in Alberta in 2012

Authors: Anne Grundy, Abbey Poirier, Farah Khandwala, Alison McFadden, Christine M. Friedenreich, Darren R. Brenner

The researchers wanted to find out what the risks of consuming red meat and processed meat. For men who ate red meat, the attributable risk was 13.6-17.9% than women which was 1.6-2.1%. The attrituable risk for men eating processed meats was also higher (3.2-4.8%) than in women. Eating red and processed meates are attrituable to 12% of colorectal cancers in AB¸.

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2016

Cancer incidence attributable to the use of oral contraceptives and hormone therapy in Alberta in 2012

Authors: Xin Grevers, Anne Grundy, Abbey E. Poirier, Farah Khandwala, Matthew Feldman, Christine M. Friedenreich, Darren R. Brenner

They wanted to esitmate the number of total cancers that were attributible to oral contraceptives. Relative risk and population attributable risk were taken from the literature, and it was found that 6.3% of cancers in Alberta were attributable to use of oral contraceptives. They found that the use of hormone therapy could increase cancer in the province and they warned that care should be taken before undergoing hormone therapy.

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2016

Cardiovascular disease and physical activity in adult cancer survivors: a nested, retrospective study from the Atlantic PATH cohort

Authors: Melanie Keats, Yunsong Cui, Scott Grandy, Louise Parker

This study looked at the correlation between cardiovasular disease and physical activity levels in cancer survivors. They assessed 1526 cancer survivors and 6034 control people. It was found the cancer survivors were 30% more likely to have a cardiovascular disease event and that cancer survivors were much less likely to participate in physical activity.

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2016

Cancer incidence attributable to tobacco in Alberta, Canada, in 2012

Authors: Abbey Poirier, Anne Grundy, Farah Khandwala, Sierra Tamminen, Darren Brenner

The 2012 study looked at number of site-specific cancers in Alberta that are attributable to tobacco exposure. They looked at data from the Canadian Community Health Survey between 2000-2007, which estimated prevalence of active/passive smoking. They found overall 37% pf tobacco related cancers were attributed to active tobacco smoking in 2012.

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2016

Association between Physical Activity and Health-Related Quality of Life in Adults with Type 2 Diabetes

Authors: Danielle Thiel, Fatima Al Sayah, Jeff Vallance, Steven Johnson, Jefferey Johnson

They wanted to determine the association between those who met physical activity and health-related quality of life in adults with type II diabetes. The mean age of the study group was about 65, and 45% of participants were female. It was found that the majority of the sample size did not meet guidelines for physical activity.

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2016

Design, methods and demographics from phase I of Alberta’s Tomorrow Project cohort: a prospective cohort profile

Authors: Paula J. Robson, Nathan M. Solbak, Tiffany R. Haig, Heather K. Whelan, Jennifer E. Vena, Alianu K. Akawung, William K. Rosner, Darren R. Brenner, Linda S. Cook, Ilona Csizmadi, Karen A. Kopciuk, . Elizabeth McGregor, Christine M. Friedenreich

This article describes Phase I of the ATP which looks at investigators that influence cancer and other diseases. Adults with no previous cancer were recruited and enrolled. 99% of those recruited agreed to be linked with administrative data bases. It was a very successful recruitment process.

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2016

A haplotype-based normalization technique for the analysis and detection of allele specific expression

Authors: Alan Hodgkinson, Jean-Christophe Grenier, Elias Gbeha, Philip Awadalla

The research team examined allele specific expression which can be an identifier for disease loci. They were able to sequence exomes from CARTaGENE cohort and find a significant association between the proportion of sites undergoing ASE within the genome and smoking.

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2016

Prediabetes, depressive and anxiety symptoms, and risk of type 2 diabetes: A community-based cohort study

Authors: Sonya Deschenes, Rachel Burns, Eva Graham, Norbert Schimitz

This study looked at the effect of prediabetes/depression on a diabetes risk. It seemed that prediabetes/depression interacted and resulted in a diabetes increase. Depression has doubled the risk of prediabetes progressing into full on diabetes. Anxiety has also heightned the risk of prediabetes turning into diabetes.

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2016

Rationale, design, and methods for Canadian alliance for healthy hearts and minds cohort study (CAHHM) – a Pan Canadian cohort study

Authors: Sonia S. Anand, Jack V. Tu, Philip Awadalla, Sandra Black, Catherine Boileau, David Busseuil, Dipika Desai, Jean-Pierre Després, Russell J. de Souza, Trevor Dummer, Sébastien Jacquemont, Bartha Knoppers, Eric Larose, Scott A. Lear, Francois Marcotte, Alan R. Moody, Louise Parker, Paul Poirier, Paula J. Robson, Eric E. Smith, John J. Spinelli, Jean-Claude Tardif, Koon K. Teo, Natasa Tusevljak, Matthias G. Friedrich

Canadian Alliance for Healthy Hearts and Minds (CAHHM) is a pan-Canadian, prospective, multi-ethnic cohort study being conducted in Canada. This project has sed CPTP data to help and assist it. CAHHM is a prospective cohort study which aims to examine the health of adults living in Canada.

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2016

Dietary assessment is a critical element of health research – Perspective from the Partnership for Advancing Nutritional and Dietary Assessment in Canada

Authors: Marie-Ève Labonté, Sharon I. Kirkpatrick, Rhonda C. Bell, Beatrice A. Boucher, Ilona Csizmadi, Anita Koushik, Mary R. L’Abbé, Isabelle Massarelli, Paula J. Robson, Isabelle Rondeau, Bryna Shatenstein, Amy F. Subar, and Benoît Lamarche

This was an opinion based paper which argued that while assessing dietary intakes is difficult, it`s not impossible. They believe that building capacity and funding opportunities should be readily available in order to build research. If they were to have these, there would be better understanding in Canada and elsewhere.

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