Polygenic risk scores distinguish patients from non‐affected adult relatives and from normal controls in schizophrenia and bipolar disorder multi‐affected kindreds
This study confirmed the usefulness of PRS in capturing the contribution of common genetic variants to the risk of SZ and BD in densely affected families.
Measures of excess body weight and anthropometry among adult Albertans: cross-sectional results from Alberta’s tomorrow project cohort
In this article they described the prevalence of excess body weight and abdominal obesity in participants with ATP. In this study, 76.8% of men and 59.5% of women reported a BMI of 25% or greater. As such many of the people studied were overweight and two thirds reported abdominal obesity. They will encourage the Albertans to improve their energy balance and reduce the burden of chronic disease.
Systemic use of antibiotics and risk of diabetes in adults: A nested case‐control study of Alberta’s Tomorrow Project
The study looked at the relationship between use of antibiotics and risk of diabetes. For this study they did a case control assessment and used logistical regression to determine the relationship between diabetes and antibitoics. They looked at 1676 cases and 13401 controls. They found 17.9% received more than 5 courses of antibiotics compared to 13.8% of controls. They found after adjusting for clinical and difficult-to-capture lifestyle data we found no association between systemic use of antibiotics and risk of diabetes.
Patterns and predictors of adherence to colorectal cancer screening recommendations in Alberta’s Tomorrow Project participants stratified by risk
The research team wanted to determine how colorectal cancer screening was relevant to modifiable behavior for cancer control. They looked at 9641 particpants and were grouped based on their age, family history, and etiology. Screening status was compared between enrollment and follow up to determine a screening pattern over time. It was determined that 77% of participants fell into an average-risk level, based on their age. However 90+% of people were at a higher risk based on their family history status. Many people did not do their CRC screening (less than 50%). They would have to take a closer look at the risk strata to determine how bad the risk is.
Perceived Susceptibility to Developing Cancer and Cancer Screening Behaviour: A Longitudinal Analysis of Alberta’s Tomorrow Project
Using data from the ATP cohort, this thesis asked the research questions: 1) Is PS to developing cancer associated with the incidence of mammography,
prostate-specific antigen, sigmoidoscopy, and colonoscopy screening tests? 2) Does an individual’s
perceived susceptibility affect screening behaviour differently between tests?
Association between Diet Quality and Adiposity in the Atlantic PATH Cohort
This research was done to assess the association between diet quality and adiposity. They found that the diet quality was very different among provinces, an area of concern was people who consumed only 1-2 servings of fruits/vegetables today. Adiposity was positively associated with consumption of excess meat, snack foods, sweetners, diet soft drinks, and fast food. It was shown that people who ate whole grains and green tea had lower levels of adiposity.
Cohort Profile: The Atlantic Partnership for Tomorrow’s Health (Atlantic PATH) Study
The PATH study wants to 1) develop a databank containing health/health-related measures 2) encourage/facilitate use of the databank . The idea is to provide information about risk factors for disease and then hopefully prevent it.
Relationship Between Adiponectin and apoB in Individuals With Diabetes in the Atlantic PATH Cohort
They waned to see if there was a relationship between biomarkers of apidose issue and cardiovasular comorbidities risk in BMI. They 480 people in their study, half of which were diabetic and half were not. It was found that plasma adiponectin levels were lower in diabetic patients than those who are not. Plasma apoB levels were similar between participants with and without diabetes.
Associations of Coffee, Diet Drinks, and Non-Nutritive Sweetener Use with Depression among Populations in Eastern Canada
They did a cross-sectional study to show the association between coffee/diet drinks/sweetners and depression. It was found there was a significant relationship between depression and consumption of sweetners/diet drinks. These symptoms were seen more in women than men.
Diet quality is associated with reduced incidence of cancer and self-reported chronic disease: Observations from Alberta’s Tomorrow Project
This study looked at food quality and how it is associated with risk of cancer and chronic disease. There were 25169 participants enrolled and it was found that the better the diet quality, the lower the risk of cancer.