Anthropometric changes and risk of diabetes: are there sex differences? A longitudinal study of Alberta’s Tomorrow Project
The objective this was study was see if there was an association with antropometric change and risk of diabetes. There was a positive association between anthropometric changes and risk of diabetes was found more in men than women.
Diet quality and risk factors for cardiovascular disease among South Asians in Alberta.
A retrospective analysis of data collected from 140 South Asian adults participating in the Alberta’s Tomorrow Project was conducted. Dietary intake was assessed using a questionnaire and the Healthy Eating Index (HEI) was used an indicator of overall diet quality and adherence to dietary recommendations made by Health Canada. Central obesity (70%), hypercholesterolemia (27%), and hypertension (14%) were predominant health conditions observed in the study participants.
Harmonization of the Health and Risk Factor Questionnaire data of the Canadian Partnership for Tomorrow Project: a descriptive analysis
This paper describes how data is harmonized the health and risk factor questionnare and provides an overview of information required to use the core data that has been created. The reason for the harmonization is to have a unique data set including data on health and risk factors from over 307000 Canadians.
Care quality for rheumatoid arthritis patients in Quebec
The main objectives of this study were to determine the number of CARTaGENE participants with rheumatoid arthritis that fulfilled pre-specified quality indicators and to examine the variation in DMARD use with respect to patient age,sex, education, and income. They assessed ~20000 people, and 142 rheumatoid arthritis patients. Quality Indicators that pertained to RA pharmacotheraphy and medical treatment ranged from 60-80%,. With lifestyle factors, 55% had moderate physical activity and less than 17% were reported to be smokers.
Dissecting features of epigenetic variants underlying cardiometabolic risk using full-resolution epigenome profiling in regulatory elements.
The research team looked up 1) genetic and 2) epigenetic regulation via intergrational studies. The comprehensive sequencing of regulatory elements methylomes reveals lots of information of functional variants linked genetically as well as epigentically to plasma lipid traits.
Rural‐Urban Disparities in Total Physical Activity, Body Composition, and Related Health Indicators: An Atlantic PATH Study
This study was done to compare the sociodemographic/lifestyle characteristics of urban/rural residents in Atlantic Canada. Over 17000 adults were surveyed and multi-linear/logistic regression were done. It was found that rural residents were significantly less likely to be regular or habitual drinkers. Obesity prevalence was much higher out in the Atlantic provinces.
Impact of adherence to cancer-specific prevention recommendations on subsequent risk of cancer in participants in Alberta’s Tomorrow Project.
This study wanted to see if cancer-specific recommendations actually prevented cancer. They found that those who adhered to said recommendations saw lower risk of develop cancer over time.
Fracture status in middle-aged individuals with early CKD: cross-sectional analysis of the CARTaGENE survey
In this cross-sectional analysis, the study team determined that CKD was not correlated with increase fractures, was not a modification factor between calcaneal QUS and fracture, but modified the association between clinical, pharmacological parameters and fracture.
Nuclear genetic regulation of the human mitochondrial transcriptome
They analyzed more than 11000 RNA sequencing libraries across 36 tissue/cell types and they found considerable variation in mitochondrial gene expression along the transcriptome. This was also looked at tissues and inviduals and highlighted the importance of cell-type specific and post transcriptional processes in shaping mitochondrial-encoded RNA levels.
Central body fatness is a stronger predictor of cancer risk than overall body size
They wanted to see the relationship between body size and weight distribution for cancer risk. They had a sample size of 26607 and determined that men have a 33% increased risk of cancer, while women have 22% increased risk. Essentially central adiposity appears to be a strong predictor of all-cancer risk than actual body size.