Publications

These publications are examples of research made possible with data from CanPath and its regional cohorts.

2017

Patterns and predictors of adherence to colorectal cancer screening recommendations in Alberta’s Tomorrow Project participants stratified by risk

Authors: Nathan M. Solbak, Jian-Yi Xu, Jennifer E. Vena, Ala Al Rajabi, Sanaz Vaseghi, Heather K. Whelan & S Elizabeth McGregor

The research team wanted to determine how colorectal cancer screening was relevant to modifiable behavior for cancer control. They looked at 9641 particpants and were grouped based on their age, family history, and etiology. Screening status was compared between enrollment and follow up to determine a screening pattern over time. It was determined that 77% of participants fell into an average-risk level, based on their age. However 90+% of people were at a higher risk based on their family history status. Many people did not do their CRC screening (less than 50%). They would have to take a closer look at the risk strata to determine how bad the risk is.

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2017

Perceived Susceptibility to Developing Cancer and Cancer Screening Behaviour: A Longitudinal Analysis of Alberta’s Tomorrow Project

Authors: Meghan Gilfoyle

Using data from the ATP cohort, this thesis asked the research questions: 1) Is PS to developing cancer associated with the incidence of mammography,
prostate-specific antigen, sigmoidoscopy, and colonoscopy screening tests? 2) Does an individual’s
perceived susceptibility affect screening behaviour differently between tests?

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2017

Association between Diet Quality and Adiposity in the Atlantic PATH Cohort

Authors: Vanessa DeClerq, Yunsong Cui, Trevor Dummer, Cynthia Forbes, Scott Grandy,Melanie Keats, Louise Parker, Ellen Sweeney, Zhijie Michael Yu

This research was done to assess the association between diet quality and adiposity. They found that the diet quality was very different among provinces, an area of concern was people who consumed only 1-2 servings of fruits/vegetables today. Adiposity was positively associated with consumption of excess meat, snack foods, sweetners, diet soft drinks, and fast food. It was shown that people who ate whole grains and green tea had lower levels of adiposity.

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2017

Cohort Profile: The Atlantic Partnership for Tomorrow’s Health (Atlantic PATH) Study

Authors: E Sweeney, Y Cui, V DeClercq, P Devichand, C Forbes, S Grandy, J M T Hicks, M Keats, L Parker, D Thompson, M Volodarsky, Z M Yu, T J B Dummer

The PATH study wants to 1) develop a databank containing health/health-related measures 2) encourage/facilitate use of the databank . The idea is to provide information about risk factors for disease and then hopefully prevent it.

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2017

Relationship Between Adiponectin and apoB in Individuals With Diabetes in the Atlantic PATH Cohort

Authors: Vanessa DeClerq, Yunsong Cui, Trevor Dummer, Cynthia Forbes, Scott Grandy,Melanie Keats, Louise Parker, Ellen Sweeney, Zhijie Michael Yu, Roger McLeod

They waned to see if there was a relationship between biomarkers of apidose issue and cardiovasular comorbidities risk in BMI. They 480 people in their study, half of which were diabetic and half were not. It was found that plasma adiponectin levels were lower in diabetic patients than those who are not. Plasma apoB levels were similar between participants with and without diabetes.

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2017

Associations of Coffee, Diet Drinks, and Non-Nutritive Sweetener Use with Depression among Populations in Eastern Canada

Authors: Zhijie Yu, Lousie Parker, Trevor Dummer

They did a cross-sectional study to show the association between coffee/diet drinks/sweetners and depression. It was found there was a significant relationship between depression and consumption of sweetners/diet drinks. These symptoms were seen more in women than men.

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2017

Diet quality is associated with reduced incidence of cancer and self-reported chronic disease: Observations from Alberta’s Tomorrow Project

Authors: Nathan Solbak, Jian-Yi Xu, Jennifer Vena, Ilona Csizmadi, Heather Whelan, Paula Robson

This study looked at food quality and how it is associated with risk of cancer and chronic disease. There were 25169 participants enrolled and it was found that the better the diet quality, the lower the risk of cancer.

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2017

Lead in drinking water: a response from the Atlantic PATH study

Authors: Ellen Sweeney, Zhijie Yu, Louise Parker, Trevor Dummer

Most of the people who were being observed in this study were below the maximum level for lead intake, however the few that were the outliners are still cause for concern.

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2017

Atopic dermatitis and risk of hypertension, type 2 diabetes, myocardial infarction and stroke in a cross‐sectional analysis from the Canadian Partnership for Tomorrow Project

Authors: A.M. Drucker, A. Qureshi, T. Dummer, L. Parker, W. Li

This study wanted to determine if there was an association with atopic dermatitis and hypertension/heart attack/stroke/type II diabetes. It was found in a cross-sectional study that AD is not really a major risk factor for cardiovascular disease.

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2017

Genetic variations at the human growth hormone receptor (GHR) gene locus are associated with idiopathic short stature

Authors: Christel Dias, Mara Giordano, Rosalie Frenchette, Simonetta Bellone, Constantin Polychronakos, Laurent Legault, Cheri Deal, Cynthia Goodyer

The CARTaGENE cohort looked 168 inviduals with SS, and found 95% were of European Ancestry. These data suggest that the variants identified are potentially genetic markers specifically associated with the ISS phenotype.

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