Publications

These publications are examples of research made possible with data from CanPath and its regional cohorts.

2020

Interaction of DRD2/ANKK1 Taq1A Genotype with in-Store Retail Food Environment Exposures on Diet Quality in a Cohort of Quebec Adults.

Authors: Neilsen, Han, Paquet, Portella, Ma, Dube

DRD2/ANKK1 Taq1A is associated with adaptive responses to ice cream displays and vegetable prices, suggesting a differential susceptibility to retail environment food cues.

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2019

Diet Quality among Cancer Survivors and Participants without Cancer: A Population-Based, Cross-Sectional Study in the Atlantic Partnership for Tomorrow’s Health Project

This study investigated the diet quality of cancer survivors relative to participants without cancer, overall and by cancer site and time from diagnosis. It found that there was considerable room for dietary improvement regardless of cancer status, highlighting the need for dietary interventions, especially among cancer survivors, who are at higher risk for secondary health problems.

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2019

Perceived susceptibility to developing cancer and mammography screening behaviour: a cross-sectional analysis of Alberta’s Tomorrow Project

Authors: M Gilfoyle, J Garcia, A Chaurasia, M Oremus

This article highlights the percevied suspectibility with cancer screening. It also showed there was higher perceived risk/chance of cancer was associated with mammography screening. They used an individualized approach to encourage more people to get screened.

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2019

Validation of Genome-Wide Polygenic Risk Scores for Coronary Artery Disease in French Canadians

Authors: Florian Wunnemann, Ken Sin Lo, Alexandra Langford-Avelar, David Busseuil, Marie-Pierre Dube, Jean-Claude Tardiff, Guillaume Lettre

This article looked at ways of predicting/preventing coronary artery disease. Polygenic risk scores based on the genome sequence can be a potential biomarker to predict the risk of CAD. Validation of PRS predictive power and transferability in other populations can support clinical utility.

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2019

Predictive value of quantitative ultrasound parameters in individuals with chronic kidney disease: A population-based analysis of CARTaGENE.

Authors: Louis-Charles Desbiens, Remi Goupil, Fabrice Mac-Way

This study showed that early decrease in renal function increase calcancela ultrasound parameters, QUS is associated with fracture incidence regardless of renal function, QUS underestimates fracture incidence in patients with early CKD.

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2019

Genetic and epidemiological characterization of restless legs syndrome in Québec

Authors: Fulya Akçimen, Jay P Ross, Faezeh Sarayloo, Calwing Liao, Rachel De Barros Oliveira, Jennifer A Ruskey, Cynthia V Bourassa, Patrick A Dion, Lan Xiong, Ziv Gan-Or ... Show more

This study aimed to assess these RLS predisposing genetic variants, as well as investigate the epidemiological profile and diagnostic features of individuals with RLS in the Québec population, using an interviewer-administered questionnaire

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2019

Validation of drug prescription records for senior patients in Alberta’s Tomorrow Project: Assessing agreement between two population-level administrative pharmaceutical databases in Alberta, Canada.

Authors: Ming Ye, Jennifer Vena, JY Xu, DT Eurich

This study was done to examine the pharamceutical information network (PIN) and the Alberta Blue Cross dataset to see the medical records of all senior patients in Alberta matched up. It was found that the PIN had a fairly good completing at capuring the ABC medications for senior patients in Alberta.

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2019

Anxiety and depression symptoms in adult males in Atlantic Canada with or without a lifetime history of prostate cancer

Authors: G Illie, Ellen Sweeney, R Rutledge

In this study based on prostate cancer and to examine the assoication between depression and anxiety. They looked at sample size of 6585 participants and found surivors of PCa had 2.45 or 2.05 statistically significant higher odds of screening positive for anxiety/depression

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2019

A population-based study of the associations between neighbourhood walkability and different types of physical activity in Canadian men and women.

Authors: Nichani V, Vena, J; Friedenreich, CM; Christie, C; McCormack GR

The purpose for this study was to determine whether there was difference between neighbourhood walkability differed amongst men/women. They examined perceived walkability and examined how the two sexes percevied walkability in their neighbourhoods.

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2019

Exome Sequencing in BRCA1- and BRCA2-Negative Greek Families Identifies MDM1 and NBEAL1 as Candidate Risk Genes for Hereditary Breast Cancer.

Authors: Stavros Glentis,Alexandros C. Dimopoulos, Konstantinos Rouskas, George Ntritsos, Evangelos Evangelou, Steven A. Narod, Anne-Marie Mes-Masson, William D. Foulkes, Barbara Rivera, Patricia N. Tonin, Jiannis Ragoussis, and Antigone S. Dimas

This study used CARTaGENE control data to find there relationship between the BRAC1-2 genes and breast cancer

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