Publications

These publications are examples of research made possible with data from CanPath and its regional cohorts.

2018

Physical Activity and Cancer Incidence in Alberta’s Tomorrow Project: Results from a Prospective Cohort of 26,538 Participants.

Authors: AM Barberio, CM Friedenreich, BM Lynch, KL Campbell, P Arora, DR Brenner

They were able to determine that a moderate to high level of physical activity could lead to a modest protection against the development of all cancer.

Read Publication
2018

Differences in adiposity and diet quality among individuals with inflammatory bowel disease in Eastern Canada

Authors: Vanessa DeClerq, Morgan Langille, Johan van Limbergen

This study looked at the relationship between diet quality and body composition in participants with IBD. There was a positive correlation between adiposity and those who ate processed grains, excess meats; there was a negative correlation between those who consumed lots of fruits/vegetables, whole grains. There was distinct difference in adiposity and diet quality were observed in individuals

Read Publication
2018

The Canadian Partnership for Tomorrow Project: a pan-Canadian platform for research on chronic disease prevention

Authors: Trevor J.B. Dummer, Philip Awadalla, Catherine Boileau, Camille Craig, Isabel Fortier, Vivek Goel, Jason M.T. Hicks, Sébastien Jacquemont, Bartha Maria Knoppers, Nhu Le, Treena McDonald, John McLaughlin, Anne-Marie Mes-Masson, Anne-Monique Nuyt, Lyle J. Palmer, Louise Parker, Mark Purdue, Paula J. Robson, John J. Spinelli, David Thompson, Jennifer Vena, Ma’n Zawati

In order to understand the risk factors for disease, participants across the study were recruited across 5 provinces. Body samples and physical information was collected from these people. They then harmonized this data. The hope out of this paper was that the samples afford strides in research both nationally nad internationally.

Read Publication
2018

Gene-by-environment interactions in urban populations modulate risk phenotypes

Authors: Marie-Julie Favé, Fabien C. Lamaze, David Soave, Alan Hodgkinson, Héloïse Gauvin, Vanessa Bruat, Jean-Christophe Grenier, Elias Gbeha, Kimberly Skead, Audrey Smargiassi, Markey Johnson, Youssef Idaghdour & Philip Awadalla

From ∼1000 individuals of a founder population in Quebec, we reveal a substantial impact of the environment on the transcriptome and clinical endophenotypes, overpowering that of genetic ancestry. Air pollution impacts gene expression and pathways affecting cardio-metabolic and respiratory traits, when controlling for genetic ancestry. 

Read Publication
2018

Development of an on-line interactive map to display environmental health assessments of Canadian communities: knowledge-translation to support collaborations for health

Authors: Russell Jude de Souza, Rishi Arora, Lise Gauvin, Natalie Williams, A. P. Oliveira, Dipika Desai, Daniel Corsi, SV Subramanian, A. Rana, Gillian Booth, Fahad Razak, Jeff Brook, Jack Tu, Sonia S. Anand

This report describes an on-line interactive map developed by the Canadian Alliance for Healthy Hearts and Minds. It contains information from over 2,000 communities across Canada!

Read Publication
2018

Plasma-Derived Inflammatory Proteins Predict Oral Squamous Cell Carcinoma

Authors: Kelly Vi Ping Liu, Xian Jun David Lu, Yuqi Sarah Zhu, Nhu Le, Hugh Kim, Catherine Poh

This study looked at a multiplex approach to screen plasma derived biomarkers and to examine the association of proteins with throat cancer. They looked at 260 plasma samples and they screened 82 biomarkers to look for disease.

Read Publication
2018

The author who wasn’t there? Fairness and attribution in publications following access to population biobanks

Authors: Erika Kleiderman, Amy Pack, Pascal Borry, Ma'n Zawati

This study conducted a document analysis that looked at publication ethics and authorship with population biobanks. In their findings, they reported a 3-step approach: 1) the biobank should be given proper acknowledgement 2) co-authorship should be encouraged to foster colloboration amongst researchers 3) referencing/citiations should be readily available

Read Publication
2018

Central and Brachial Blood Pressures, Statins, and Low-Density Lipoprotein Cholesterol

Authors: Florence Lamarche, Mohsen Agharazii, Annie-Claire Nadeau-Fredette, Francois Madore, Remi Goupii

This study wanted to characterize the association of stains and LDL-c with central and brachial blood pressures and to quantify their respective effects. They looked 20004 partcipants, and 16507 of them had available central blood pressure. In conclusion, reduction of LDL-c was associated with only a fraction of the lower blood pressures in statin user and seemed to be mostly associated with improvement of steady (diastolic) pressure, whereas non–LDL-c–mediated pathways were mostly associated with changes in pulsatile pressure components.

Read Publication
2018

Associations Between Depressive Symptoms and Indices of Obesity in Adults With Prediabetes and Normal Blood Glucose Levels: Results From the Emotional Health and Wellbeing Study

Authors: Rachel Burns, Soyna Deschenes, Norbert Schmitz

Depressive symptoms are associated with higher incident rates of dibaetes, but they are not sure if depressive symptoms are linked to prediabetes. The results from this study showed that there was depressive symptoms were positively associated with BMI, fat mass index, waist circumfrence in prediabetic adults. The assoications observed in people with prediabetes were stronger than those observed with normal blood glucose levels.

Read Publication
2018

The 2017 American College of Cardiology/American Heart Association vs Hypertension Canada High Blood Pressure Guidelines and Potential Implications

Authors: Remi Goupil, Maxime Lamarre-Cliché, Michel Vallee

This report compared the American and Canadian guidelines of Hypertension Canada and American College of Cardiology and American Heart Association and found that compared to the ACC/AHA guidelines it would result in increases of 8.7% in hypertension diagnosis and 3.4% of individuals needing treatment with 17.2% having a different BP target.

Read Publication