Associations Between Depressive Symptoms and Indices of Obesity in Adults With Prediabetes and Normal Blood Glucose Levels: Results From the Emotional Health and Wellbeing Study
Depressive symptoms are associated with higher incident rates of dibaetes, but they are not sure if depressive symptoms are linked to prediabetes. The results from this study showed that there was depressive symptoms were positively associated with BMI, fat mass index, waist circumfrence in prediabetic adults. The assoications observed in people with prediabetes were stronger than those observed with normal blood glucose levels.
Genetic variations at the human growth hormone receptor (GHR) gene locus are associated with idiopathic short stature
The CARTaGENE cohort looked 168 inviduals with SS, and found 95% were of European Ancestry. These data suggest that the variants identified are potentially genetic markers specifically associated with the ISS phenotype.
Industrial air emissions, and proximity to major industrial emitters, are associated with anti-citrullinated protein antibodies
They assessed the relationships between PM25, SO2, and ACPA which is a marker for RA, they found there was a positive association between ACPA and industrial PM2.5/SO2 emissions. Finally there was a correlation between air pollution from industrial emissions and ACPA suggests a role for these exposures in RA.
Prediabetes, depressive and anxiety symptoms, and risk of type 2 diabetes: A community-based cohort study
This study looked at the effect of prediabetes/depression on a diabetes risk. It seemed that prediabetes/depression interacted and resulted in a diabetes increase. Depression has doubled the risk of prediabetes progressing into full on diabetes. Anxiety has also heightned the risk of prediabetes turning into diabetes.
Rationale, design, and methods for Canadian alliance for healthy hearts and minds cohort study (CAHHM) – a Pan Canadian cohort study
Canadian Alliance for Healthy Hearts and Minds (CAHHM) is a pan-Canadian, prospective, multi-ethnic cohort study being conducted in Canada. This project has sed CPTP data to help and assist it. CAHHM is a prospective cohort study which aims to examine the health of adults living in Canada.
Maelstrom Research guidelines for rigorous retrospective data harmonization
This article looked at the best ways to do data harmonization. By adhering to the proposed guidelines, the researchers sought to find the best way getting clean data. They found that by adhering to the guidelines, data harmonization can be easier to undertake.
Depression and risk of type 2 diabetes: the potential role of metabolic factors
This study looked at the interaction between depressive symptoms and metabolic dysregulations as risk factors for type II diabetes. The study found depressive symptoms and disruptions in metabolic regulation can lead to risk of type two diabetes.
Replication study of MATR3 in familial and sporadic amyotrophic lateral sclerosis
In this study, they looked at mutations of MATR3 (gene that is associated with ALS). They assessed the frequency in French Canadian populations and had a control group. They were able to determine which proteins are associated with ALS.
Comparison of the Effect of Thiazide Diuretics and Other Antihypertensive Drugs on Central Blood Pressure: Cross‐Sectional Analysis Among Nondiabetic Patients
This study used CARTaGENE data to determine to assess the noninferority of TDs relative to different classes of antihypertensive medications in relation to central blood pressure. No major differences were noted and it was shown that TDs are at least as effective as other first line medications that are available.
Association of age-dependent height and bone mineral density decline with increased arterial stiffness and rate of fractures in hypertensive individuals
They wanted to determine if there was an association with height, arterial stiffness, and bone fractures. They were able to determine at the end of the study that those with shorter statures were more likely to have arterial stiffness and hypertension.