Publications

These publications are examples of research made possible with data from CanPath and its regional cohorts.

2021

Examining the etiology of early-onset breast cancer in the Canadian Partnership for Tomorrow’s Health (CanPath)

Authors: Joy Pader, Robert Basmadjian, Dylan O'Sullivan, Nicole Mealey, Yibing Ruan, Christine Friedenreich, Rachel Murphy, Edwin Wang, May Lynn Quan, Darren Brenner

The objective of this study was to investigate relationships between modifiable and non-modifiable risk factors and early-onset breast cancer among the BC Generations Project, Alberta’s Tomorrow Project and Ontario Health Study. In this study, measures of adiposity, pregnancy history, and familial history of breast cancer are important risk factors for early-onset breast cancer.

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2021

Dietary patterns with combined and site-specific cancer incidence in Alberta’s Tomorrow Project cohort

Authors: Romy Willemsen, Jessica McNeil, Emily Heer, Steven Johnson, Christine Fredenreich, Darren Brenner

This study used data from the Alberta’s Tomorrow Project to examine the association between dietary patterns derived with two methods, and combined and site-specific cancer incidence in Canada.

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2020

Diabetes, Brain Infarcts, Cognition and Small Vessels in the Canadian Alliance for Healthy Hearts and Minds Study

Authors: Hertzel Gerstein, Eric Smith, Chinthanie Ramasundarahettige, Dipika Desai, Philip Awadalla, Philippe Broet, Sandra Black, Trevor Dummer, Jason Hicks, Alan Moody, Jean-Claude Tardif, Koon Teo, Jennifer Vena, Salim Yusuf, Douglas Lee, Matthias Friedrich, Sonia Anand

The CAHHM study collected brain and carotid magnetic resonance imaging (MRI) and two cognitive tests (DSST and MoCA) in a cross-sectional sample of 7,733 men and women. It was concluded that small vessel disease characterizes much of the relationship between diabetes and vascular brain injury. However, additional factors are required to disentangle the relationship between diabetes and cognitive impairment.

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2019

Validation of drug prescription records for senior patients in Alberta’s Tomorrow Project: Assessing agreement between two population-level administrative pharmaceutical databases in Alberta, Canada.

Authors: Ming Ye, Jennifer Vena, JY Xu, DT Eurich

This study was done to examine the pharamceutical information network (PIN) and the Alberta Blue Cross dataset to see the medical records of all senior patients in Alberta matched up. It was found that the PIN had a fairly good completing at capuring the ABC medications for senior patients in Alberta.

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2019

Anthropometric changes and risk of diabetes: are there sex differences? A longitudinal study of Alberta’s Tomorrow Project

Authors: Ming Ye, Paula Robson, Dean Eurich, Jennifer Vena, Jian-Yi Xu, Jefferey A Johnson

The objective this was study was see if there was an association with antropometric change and risk of diabetes. There was a positive association between anthropometric changes and risk of diabetes was found more in men than women.

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2018

Physical Activity and Cancer Incidence in Alberta’s Tomorrow Project: Results from a Prospective Cohort of 26,538 Participants.

Authors: AM Barberio, CM Friedenreich, BM Lynch, KL Campbell, P Arora, DR Brenner

They were able to determine that a moderate to high level of physical activity could lead to a modest protection against the development of all cancer.

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2017

Diet quality is associated with reduced incidence of cancer and self-reported chronic disease: Observations from Alberta’s Tomorrow Project

Authors: Nathan Solbak, Jian-Yi Xu, Jennifer Vena, Ilona Csizmadi, Heather Whelan, Paula Robson

This study looked at food quality and how it is associated with risk of cancer and chronic disease. There were 25169 participants enrolled and it was found that the better the diet quality, the lower the risk of cancer.

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2017

Changes in body mass index and incidence of diabetes: A longitudinal study of Alberta’s Tomorrow Project Cohort

Authors: Ming Ye, Paula Robson, Dean Eurich, Jennifer Vena, Jian-Yi Xu, Jefferey A Johnson

The study objective was to figure out the association between BMI changes over a given period of time, and the number of new diabetes cases. When there was a BMI increase, there was a higher risk of developing diabetes and with the BMI reduction, there was lower risk of diabetes. This was the case for the those who were overweight, there was no association with underweight or normal BMI populations.

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2017

The Comparative Reliability and Feasibility of the Past-Year Canadian Diet History Questionnaire II: Comparison of the Paper and Web

Authors: Geraldine Lo Siou, Ilona Cszimadi, Beatrice Boucher, Alianu Akawung, Heather Whelan, Michelle Sharma, Ala Al Rajabi, Jennifer Vena, Sharon Kirkpatrick, Anita Koushik, Isabelle Massarelli, Isabelle Rondreau, Paula Robson

This study looked at evaluating the intra-and inter-version reliability, feasability, and accetability of the Canadian Diet History Questionnaire II in a sub-sample of 648 adults. They were assigned either web or paper, 59% preferred the web version.

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2017

Lessons from Studies to Evaluate an Online 24-Hour Recall for Use with Children and Adults in Canada

Authors: Sharon Kirkpatrick, Anne Gilsing, Erin Hobbin, Nathan Solbak, Angela Wallace, Jess Haines, Alexandra Mayhew, Sarah Orr, Parminder Raina, Paula Robson, Jocelyn Sacco, Heather Whelan

This team looked at the Automated Self-Administered 24-h assessment tool and looked at 5 studies that looked at feasibility and accessibility There was a high acceptance of ADA24 in diverse samples but it was not always intuitive for everyone (kids and older adults).

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