Cohort Profile: Alberta’s Tomorrow Project
This article outlined the rationale as to why the it was necessary to set up a large cohort in Alberta and it aruged its feasiblity in the CPTP project. They argued that the project has many strengths and the research that came out of it but also said that it has had some problems with its recruting phase. Finally the article outlined how the data can be obtained, and discussed its funding.
Cancer incidence attributable to red and processed meat consumption in Alberta in 2012
The researchers wanted to find out what the risks of consuming red meat and processed meat. For men who ate red meat, the attributable risk was 13.6-17.9% than women which was 1.6-2.1%. The attrituable risk for men eating processed meats was also higher (3.2-4.8%) than in women. Eating red and processed meates are attrituable to 12% of colorectal cancers in AB¸.
Cancer incidence attributable to the use of oral contraceptives and hormone therapy in Alberta in 2012
They wanted to esitmate the number of total cancers that were attributible to oral contraceptives. Relative risk and population attributable risk were taken from the literature, and it was found that 6.3% of cancers in Alberta were attributable to use of oral contraceptives. They found that the use of hormone therapy could increase cancer in the province and they warned that care should be taken before undergoing hormone therapy.
Cardiovascular disease and physical activity in adult cancer survivors: a nested, retrospective study from the Atlantic PATH cohort
This study looked at the correlation between cardiovasular disease and physical activity levels in cancer survivors. They assessed 1526 cancer survivors and 6034 control people. It was found the cancer survivors were 30% more likely to have a cardiovascular disease event and that cancer survivors were much less likely to participate in physical activity.
Cancer incidence attributable to tobacco in Alberta, Canada, in 2012
The 2012 study looked at number of site-specific cancers in Alberta that are attributable to tobacco exposure. They looked at data from the Canadian Community Health Survey between 2000-2007, which estimated prevalence of active/passive smoking. They found overall 37% pf tobacco related cancers were attributed to active tobacco smoking in 2012.
Association between Physical Activity and Health-Related Quality of Life in Adults with Type 2 Diabetes
They wanted to determine the association between those who met physical activity and health-related quality of life in adults with type II diabetes. The mean age of the study group was about 65, and 45% of participants were female. It was found that the majority of the sample size did not meet guidelines for physical activity.
Design, methods and demographics from phase I of Alberta’s Tomorrow Project cohort: a prospective cohort profile
This article describes Phase I of the ATP which looks at investigators that influence cancer and other diseases. Adults with no previous cancer were recruited and enrolled. 99% of those recruited agreed to be linked with administrative data bases. It was a very successful recruitment process.
A haplotype-based normalization technique for the analysis and detection of allele specific expression
The research team examined allele specific expression which can be an identifier for disease loci. They were able to sequence exomes from CARTaGENE cohort and find a significant association between the proportion of sites undergoing ASE within the genome and smoking.
Prediabetes, depressive and anxiety symptoms, and risk of type 2 diabetes: A community-based cohort study
This study looked at the effect of prediabetes/depression on a diabetes risk. It seemed that prediabetes/depression interacted and resulted in a diabetes increase. Depression has doubled the risk of prediabetes progressing into full on diabetes. Anxiety has also heightned the risk of prediabetes turning into diabetes.
Rationale, design, and methods for Canadian alliance for healthy hearts and minds cohort study (CAHHM) – a Pan Canadian cohort study
Canadian Alliance for Healthy Hearts and Minds (CAHHM) is a pan-Canadian, prospective, multi-ethnic cohort study being conducted in Canada. This project has sed CPTP data to help and assist it. CAHHM is a prospective cohort study which aims to examine the health of adults living in Canada.