Lead in drinking water: a response from the Atlantic PATH study
Most of the people who were being observed in this study were below the maximum level for lead intake, however the few that were the outliners are still cause for concern.
Atopic dermatitis and risk of hypertension, type 2 diabetes, myocardial infarction and stroke in a cross‐sectional analysis from the Canadian Partnership for Tomorrow Project
This study wanted to determine if there was an association with atopic dermatitis and hypertension/heart attack/stroke/type II diabetes. It was found in a cross-sectional study that AD is not really a major risk factor for cardiovascular disease.
Genetic variations at the human growth hormone receptor (GHR) gene locus are associated with idiopathic short stature
The CARTaGENE cohort looked 168 inviduals with SS, and found 95% were of European Ancestry. These data suggest that the variants identified are potentially genetic markers specifically associated with the ISS phenotype.
Allele-specific expression reveals interactions between genetic variation and environment
Combining whole-blood RNA-seq with extensive environmental annotations collected from 922 human individuals, we identified 35 GxE interactions, compared with only four using standard GxE interaction testing. EAGLE provides new opportunities for researchers to identify GxE interactions using functional genomic data.
Industrial air emissions, and proximity to major industrial emitters, are associated with anti-citrullinated protein antibodies
They assessed the relationships between PM25, SO2, and ACPA which is a marker for RA, they found there was a positive association between ACPA and industrial PM2.5/SO2 emissions. Finally there was a correlation between air pollution from industrial emissions and ACPA suggests a role for these exposures in RA.
Changes in body mass index and incidence of diabetes: A longitudinal study of Alberta’s Tomorrow Project Cohort
The study objective was to figure out the association between BMI changes over a given period of time, and the number of new diabetes cases. When there was a BMI increase, there was a higher risk of developing diabetes and with the BMI reduction, there was lower risk of diabetes. This was the case for the those who were overweight, there was no association with underweight or normal BMI populations.
Multimorbidity in Atlantic Canada and association with low levels of physical activity
It was reported that 38% of participants had 2 or more chronic diseases and women were more likely to be affected. People with multimorbid individuals were more likely to be inactive. It is important to implement physical activity prescription.
Inherited Chromosomally Integrated Human Herpesvirus 6 and Breast Cancer
There is a condition that affects 1% of the population where iciHHV-6 and they wanted to do know if such a mutation predisposes a person to cancer development. They found there was no statistically significant association between HHV-6 and breast cancer in women.
Deep genealogical analysis of a large cohort of participants in the CARTaGENE project (Quebec, Canada)
The main objective of this study was to reconstruct, analyse, and compare ascending genologies of participants to CARTaGENE. They found 5110 genealogies were from four Quebec regions were constructed. They were able to find ancestry going back to the 17th century.
Self-Report Dietary Assessment Tools Used in Canadian Research: A Scoping Review
This study did a scoping review of the literature using several search engines. They looked at different food frequencies and 24 recalls. Dietary was a big measurement of this study and they said that ways to improve the application of current evidence on best practices in dietary assessment have the potential to support a stronger literature for diet and health.