Investigating associations between anti-nuclear antibody positivity and combined long-term exposures to NO2, O3, and PM2.5 using a Bayesian kernel machine regression approach.
This group determined ANA using biobanked sera, they asssesed the effects of exposures to NO2 and O3 and PM2.5, they compared the results obtained by the BKMR to standard logistic regression models
Incidence of fractures in middle-aged individuals with early chronic kidney disease: a population-based analysis of CARTaGENE
This article looked at the the number of new fractures with people in the CARTaGENE cohort that were affected with CKD
Validation of Genome-Wide Polygenic Risk Scores for Coronary Artery Disease in French Canadians
This article looked at ways of predicting/preventing coronary artery disease. Polygenic risk scores based on the genome sequence can be a potential biomarker to predict the risk of CAD. Validation of PRS predictive power and transferability in other populations can support clinical utility.
Predictive value of quantitative ultrasound parameters in individuals with chronic kidney disease: A population-based analysis of CARTaGENE.
This study showed that early decrease in renal function increase calcancela ultrasound parameters, QUS is associated with fracture incidence regardless of renal function, QUS underestimates fracture incidence in patients with early CKD.
Genetic and epidemiological characterization of restless legs syndrome in Québec
This study aimed to assess these RLS predisposing genetic variants, as well as investigate the epidemiological profile and diagnostic features of individuals with RLS in the Québec population, using an interviewer-administered questionnaire
The Establishment of the Household Air Pollution Consortium (HAPCO)
This article looked at some of the dangers surrounding household air pollution and and it’s association with lung cancer. The Household Air Pollution Consortium will make sure that there is research being done to address public health concerns associated with HAP.
Dissecting features of epigenetic variants underlying cardiometabolic risk using full-resolution epigenome profiling in regulatory elements.
The research team looked up 1) genetic and 2) epigenetic regulation via intergrational studies. The comprehensive sequencing of regulatory elements methylomes reveals lots of information of functional variants linked genetically as well as epigentically to plasma lipid traits.
Green space associations with mental health and cognitive function
This study was done so that they could determine the relationship between mental health and access to green space. They enrolled 8144 people and used questionnares to measure any depression/anxiety. They found that while urban green space affords a lower depression score, it does not affect cognitive function.
Uromodulin in a Pathway Between Decreased Renal Urate Excretion and Albuminuria
The study team evaluated the impact of candidate variants in the main urate transporter genes, and also they examined the urumodulin/sodium excretion as mediators of the association between FEUA and uACR. Out of the 737 participants, 593 were observed in the final analysis. They found that there was an association between albuminuria with decreased renal urate excretion may be modified by the transporter SLC2A9.
Environmental health assessment of communities across Canada: contextual factors study of the Canadian Alliance for Healthy Hearts and Minds
This study aimed to report national-level community characteristics and any interprovincial, urban/rural, and Cartesian coordinate differences. Researchers developed an on-line map for public use, showing differences in fruit and vegetable availability, advertising for sweet drinks, junk food, and tobacco products, and cigarette and alcohol prices.