Publications

Negative Association of Smoking History With Clinically Manifest Cardiac Sarcoidosis: A Case-Control Study

Authors: Chenchen Xu, Pablo B Nery, Christiane Wiefels, Rob S Beanlands, Stewart D Spence, Daniel Juneau, Steven Promislow, Kevin Boczar, Robert A deKemp, David H Birnie

Researchers aimed to explore whether smoking was associated with a specific sarcoidosis phenotype, primarily in Caucasian patients with clinically manifest cardiac sarcoidosis (CS). Ontario Health Study participants’ data were used as controls, while the cases came from the Cardiac Sarcoidosis Multi-Center Prospective Cohort Study. They found a strong association between smoking history and clinically manifest CS, but more research is required to understand whether these associations have therapeutic potential.