Publications

These publications are examples of research made possible with data from CanPath and its regional cohorts.

2011

Hours spent and energy expended in physical activity domains: Results from The Tomorrow Projectcohort in Alberta, Canada

Authors: Ilona Cszimadi, Geraldine Lo Siou, Christine Friedenreich, Neville Owen, Paula Robson

A survey called Past Year Total Physical Activity Questionnaire had 15591 participants that dealt with the amount of phyiscal activity each person got. Those who were considered inactive got most of their activty at work. One suggestion was that environmental and policy changes could be amended so that more energy could be expended, and there would be less sitting time.

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2011

From consent to institutions: Designing adaptive governance for genomic biobanks

Authors: Kieran C.O’Doherty, Michael M.Burgess, KellyEdwards, Richard P.Gallagherd, Alice K.Hawkins, Jane Kayee VeronicaMcCaffrey David E.Winickoff

This paper outlined four principles regarding biobank governance: 1) recognizing participants as one entity 2) integrity 3) adaptive management 4) fit between the nature of a particular biobank and the specific structural elements of governance adopted. BC Generations was a working model for further discussion the outlines of the proposed governance.

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2011

Potential novel candidate polymorphisms identified in genome-wide association study for breast cancer susceptibility

Authors: Badan Sehrawat, Malinee Sridharan, Sunita Ghosh, Paula Robson, Carol E. Cass, John R. Mackey, Russell Greiner,Sambasivarao, Damaraju

They performed a two-stage association study with a cohort of 3064 women . They did two various stages of the study. Stage I was looking at single nucleotide polymorphisms and Stage II was replicating specific markers from stage I. After doing the two stages they were able to identify various genetic regions and the SNPs discssed could serve as a potential candidate loci for breast cancer in another replication study.

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2011

Exploring Statistical Approaches to Diminish Subjectivity of Cluster Analysis to Derive Dietary Patterns: The Tomorrow Project 

Authors: Geraldine Lo Siou, Yutaka Yasui, Ilona Csizmadi, Elizabeth McGregor, Paula Robson

The reseachers wanted to explore dietary patterns, so they did a food frequency questionnaire of 6445 men and 10299 women. An analysis was done which looked at proteins, fats, and calories and the information was compiled using a clustering method.

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2011

Access Arrangements’ for Biobanks: A Fine Line between Facilitating and Hindering Collaboration

Authors: S. Fortini, S. Pathmasiri, R. Grintuch, M. Deschenes

This paper looked at how access arrangements identify key elements of these new regulatory instruments. It also looks at the different ways biobanks regulate access and surveys, it also outlines the challenges involved with creating access policy with CARTaGENE.

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2011

Cohorts and consortia conference: a summary report (Banff, Canada, June 17–19, 2009)

Authors: Paolo Boffetta, Graham Colditz, John Potter, Laurence Kolonel, Paula Robson, Reza Malekzadeh, Daniela Seminara, Ellen Goode, Keun-Young Yoo, Paul Demers, Richard Gallagher, Ross Prentice, Yutaka Yasui, Kieran O'Doherty, Gloria Petersen

This discussed how various cohort studies can build a strong network of research.

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2010

The Canadian Partnership for Tomorrow Project: building a pan-Canadian research platform for disease prevention

Authors: Marilyn J. Borugian, Paula Robson, Isabel Fortier, Louise Parker, John McLaughlin, Bartha Maria Knoppers, Karine Bédard, Richard P. Gallagher, Sandra Sinclair, Vincent Ferretti, Heather Whelan, David Hoskin and John D. Potter

This article outlines the challenges a pan-Canadian cohort to look at cancer and chronic disease. The hope of this cohort will be that it could be a major research platform for the study of disease causation nationally, and internationally. They outlined how they got their participants, which provinces are involved, and how this specific cohort is unique.

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2010

Quality, quantity and harmony: the DataSHaPER approach to integrating data across bioclinical studies

Authors: Isabel Fortier, Paul R Burton, Paula J Robson, Vincent Ferretti, Julian Little, Francois L’Heureux, Mylène Deschênes, Bartha M Knoppers, Dany Doiron, Joost C Keers, Pamela Linksted, Jennifer R Harris, Geneviève Lachance, Catherine Boileau, Nancy L Pedersen, Carol M Hamilton, Kristian Hveem, Marilyn J Borugian, Richard P Gallagher, John McLaughlin, Louise Parker, John D Potter, John Gallacher, Rudolf Kaaks, Bette Liu, Tim Sprosen, Anne Vilain, Susan A Atkinson, Andrea Rengifo, Robin Morton, Andres Metspalu, H Erich Wichmann, Mark Tremblay, Rex L Chisholm, Andrés Garcia-Montero, Hans Hillege, Jan-Eric Litton, Lyle J Palmer, Markus Perola, Bruce HR Wolffenbuttel, Leena Peltonen, Thomas J Hudson

The DataSHaPER is being used with CPTP to integrate their data in a way that it can easily be harmonized and pooled together.

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2010

The Epidemiology of Weight Perception: Perceived Versus Self-reported Actual Weight Status among Albertan Adults

Authors: J Linder, L McLaren, G Siou, I Cszimadi, P Robson

They analyzed data from the Tomorrow Project from 7436 people in Alberta between the ages of 35-69 which looked at weight perception accuracy. It seemed that women were more accurate about determining whether they were overweight or not, whereas the men were not always aware.

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2008

Sociodemographic, health and lifestyle characteristics reported by discrete groups of adult dietary supplement users in Alberta, Canada: findings from The Tomorrow Project

Authors: Paula Robson, Geraldine Lo Siou, Heather Bryant

The rationale behind this study was to see the differences in sociodemographic, lifestyle, or dietary characteristics exist between the different tpyes of dietary supplements and supplement non-users. They looked at 5067 men and 7439 women and found supplement use was at 69.8%. By dividing participants as supplement users or non-users, it would mask further differences in sociodemographic dietary and lifestyle chracteristics in the various types of supplements.

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