An examination of the role of socioeconomic status in the relationship between depression and prostate cancer survivorship in a population-based sample of men from Atlantic Canada
This study found that the association of depression and prostate cancer still stands when the survivors of prostate cancer are compared to survivors of any other form of cancer, and further indicates that the association is moderated by household income.
Administering a combination of online dietary assessment tools, the Automated Self-Administered 24-Hour Dietary Assessment Tool and Diet History Questionnaire-II, in a cohort of adults in Alberta’s Tomorrow Project
This study determined the feasibility and acceptability of combining the ASA24-2016 and the past-year Diet History Questionnaire web-based tools in a subset of participants in the ATP cohort. The study found that combining ASA24-2016 recalls and the DHQ-II is feasible in this group of ATP participants.
Common variants in the CD36 gene are associated with dietary fat intake, high-fat food consumption and serum triglycerides in a cohort of Quebec adults
This study found that CD36 variants are associated with habitual fat consumption, which may play a role in subsequent associations with chronic-disease biomarkers. Associations differ by BMI status and dietary fat type.
Predictors of long-term use of prescription opioids in the community-dwelling population of adults without a cancer diagnosis: a retrospective cohort study
This study aimed to identify risk factors for and predictors of long-term use of prescription opioids in the community-dwelling population of adults without a diagnosis of cancer, to inform practice change at the point of care. It was found that limiting the initial supply to no more than 7 days and limiting doses to 90 MME/day or less are actions that could be undertaken at the point of care to prevent long-term use.
Investigating the causal role of MRE11A p.E506* in breast and ovarian cancer
This study investigated if MRE11A is a true predisposition gene for hereditary breast and ovarian cancer. Investigations suggested that the identified variant is not associated with an increased risk of developing breast or ovarian cancer, and suggests a lack of clinical utility of MRE11A testing in HBOC, at least in the White/Caucasian populations.
Regional Comparisons of Associations between Physical Activity Levels and Cardiovascular Disease: The Story of Atlantic Canada
The study examined participants’ physical activity levels and the risk of cardiovascular disease based on the region they lived in. The research team found that high physical activity was associated with a 26% reduced risk of cardiovascular disease. Regions in Newfoundland and New Brunswick observed higher levels of CVD than Nova Scotia and PEI.
Associations between cognitive function, metabolic factors and depression: A prospective study in Quebec, Canada
The study used baseline and follow-up CARTaGENE data to assess the potential interactions between low cognitive function, metabolic risk factors and history of depression as risk factors for future depressive episodes. Participants with a comorbidity of at least one metabolic factor, history of depression and low cognitive function were found to have the highest risk of experiencing a depressive episode in middle age.
Agreement in the CARTaGENE cohort between self-reported medication use and claim data
The research team investigated the agreement of self-reported medication use in CARTaGENE baseline data with provincial health insurance records. Overall, there was a reasonable agreement between the two data sources, but important variations were found for the different drug classes.
Normal sex and age-specific parameters in a multi-ethnic population: a cardiovascular magnetic resonance study of the Canadian Alliance for Healthy Hearts and Minds cohort
Researchers sought to create a robust, reference value set for cardiovascular magnetic resonance (CMR) parameters, and understand their relationship with age and sex in people without cardiovascular disease (CVD) history or risk factors. They were able to uncover a significant influence of sex and age on these parameters for use in clinical evaluations of CVD.
Social Jetlag and Prostate Cancer Incidence in Alberta’s Tomorrow Project: A Prospective Cohort Study
Social jetlag has been linked with obesity, metabolic disorders, and cardiovascular risk in previous research. This study assessed social jetlag in 7455 cancer-free men in Alberta’s Tomorrow Project and followed them for on average 9.6 years, 250 men were diagnosed with prostate cancer. The study found that the more social jetlag men experienced, the greater their prostate cancer risk was.