Publications

Les publications qui suivent sont des exemples de recherches rendues possibles grâce aux données de CanPath et de ses cohortes régionales.

2024

Genomic Analysis Identifies Risk Factors in Restless Legs Syndrome

Auteurs : Fulya Akçimen, Ruth Chia, Sara Saez-Atienzar, Paola Ruffo, Memoona Rasheed, Jay P. Ross, Calwing Liao, Anindita Ray, Patrick A. Dion, Sonja W. Scholz , Guy A. Rouleau, and Bryan J. Traynor

The researchers studied 9,851 Restless Legs Syndrome (RLS) cases and 38,957 controls of European ancestry from CARTaGENE, Canadian Longitudinal Study on Aging, and All of Us biobanks in Canada and the U.S. They found nine genetic locations linked to RLS, including one new location (LMX1B), and identified two related genes (GLO1 and ELFN1). The study also revealed genetic overlaps between RLS and traits like neuroticism, depression, and intelligence. This research enhances our understanding of RLS’s genetic factors.

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