Breast cancer prediction using genome wide single nucleotide polymorphism data
These researchers studied 696 female participants and used an SNC model to determine whether a new subject would develop breast cancer or not.
Prevalence of meeting physical activity guidelines for cancer prevention in Alberta
They looked at the guidelines for physical activity of 14294 particpants between the ages of 35-64 and found 23-55% of participants met the guidelines, depending on which one they were being measured against (CSEP, ACS, USDHHS, WCRF/AICR). Women were less likely to reach certain guidelines than men were. Study concluded that people in Alberta, mostly women were not active enough for cancer prevention benefits.
A two-stage association study identifies methyl-CpG-binding domain protein 2 gene polymorphisms as candidates for breast cancer susceptibility
This study looked at a two-stage association design using markers from a genome-wide study. They restricted their analysis to DNA polymorphisms and selected 22 SNPS. There were certain SNPs that were found to be relevant to breast cancer susceptibility in populations.
Hours spent and energy expended in physical activity domains: Results from The Tomorrow Projectcohort in Alberta, Canada
A survey called Past Year Total Physical Activity Questionnaire had 15591 participants that dealt with the amount of phyiscal activity each person got. Those who were considered inactive got most of their activty at work. One suggestion was that environmental and policy changes could be amended so that more energy could be expended, and there would be less sitting time.
Potential novel candidate polymorphisms identified in genome-wide association study for breast cancer susceptibility
They performed a two-stage association study with a cohort of 3064 women . They did two various stages of the study. Stage I was looking at single nucleotide polymorphisms and Stage II was replicating specific markers from stage I. After doing the two stages they were able to identify various genetic regions and the SNPs discssed could serve as a potential candidate loci for breast cancer in another replication study.
Exploring Statistical Approaches to Diminish Subjectivity of Cluster Analysis to Derive Dietary Patterns: The Tomorrow Project
The reseachers wanted to explore dietary patterns, so they did a food frequency questionnaire of 6445 men and 10299 women. An analysis was done which looked at proteins, fats, and calories and the information was compiled using a clustering method.
The Canadian Partnership for Tomorrow Project: building a pan-Canadian research platform for disease prevention
This article outlines the challenges a pan-Canadian cohort to look at cancer and chronic disease. The hope of this cohort will be that it could be a major research platform for the study of disease causation nationally, and internationally. They outlined how they got their participants, which provinces are involved, and how this specific cohort is unique.
Quality, quantity and harmony: the DataSHaPER approach to integrating data across bioclinical studies
The DataSHaPER is being used with CPTP to integrate their data in a way that it can easily be harmonized and pooled together.
The Epidemiology of Weight Perception: Perceived Versus Self-reported Actual Weight Status among Albertan Adults
They analyzed data from the Tomorrow Project from 7436 people in Alberta between the ages of 35-69 which looked at weight perception accuracy. It seemed that women were more accurate about determining whether they were overweight or not, whereas the men were not always aware.
Sociodemographic, health and lifestyle characteristics reported by discrete groups of adult dietary supplement users in Alberta, Canada: findings from The Tomorrow Project
The rationale behind this study was to see the differences in sociodemographic, lifestyle, or dietary characteristics exist between the different tpyes of dietary supplements and supplement non-users. They looked at 5067 men and 7439 women and found supplement use was at 69.8%. By dividing participants as supplement users or non-users, it would mask further differences in sociodemographic dietary and lifestyle chracteristics in the various types of supplements.