Search results Showing 10 of 10 results for “breast cancer”
Mental health, cancer risk, and the mediating role of lifestyle factors in the CARTaGENE cohort study
…disorders, all cancers, and lung cancer risk, except for anxiety and lung cancer in women, where associations were lower when adjusting for sociodemographics, health and lifestyle. The study also found…
A comprehensive analysis of skin cancer concerns and protective practices in Manitoba, Canada, highlights lack of skin cancer awareness and predominance of high-risk sun exposure behaviors
…fewer than 50% used sunscreen. These findings highlight critical gaps in sun protection practices and awareness, underscoring the urgent need for targeted public health interventions to reduce skin cancer rates….
The mediating role of health behaviors in the association between depression, anxiety and cancer incidence: An individual participant data meta-analysis
…Health, Ontario Health Study, and CARTaGENE. The findings suggested that smoking serves as a mediating factor that connects depression and anxiety with lung cancer and other cancers related to smoking….
Depression, anxiety, and the risk of cancer: An individual participant data meta-analysis
…anxiety, and the incidence of various cancer types. They found that depression and anxiety are not related to increased risk for most cancer outcomes, except for lung and smoking-related cancers….
A functionally impaired missense variant identified in French Canadian families implicates FANCI as a candidate ovarian cancer-predisposing gene
…describe how new genes might be associated with ovarian cancer risk amongst 5,249 CARTaGENE participants. They found that a FANCI gene mutation is more common in familial ovarian cancer patients….
The National Cancer Institute Cohort Consortium: An International Pooling Collaboration of 58 Cohorts from 20 Countries
The NCI Cohort Consortium was founded in 2001 and brings together 58 cancer epidemiology cohorts from 20 countries to undertake large-scale pooling research. This article outlines the structure, governance, methods…
Perceived Susceptibility to Developing Cancer and Cancer Screening Behaviour: A Longitudinal Analysis of Alberta’s Tomorrow Project
Using data from the ATP cohort, this thesis asked the research questions: 1) Is PS to developing cancer associated with the incidence of mammography, prostate-specific antigen, sigmoidoscopy, and colonoscopy screening…
Molecular Genetic Characteristics of FANCI, a Proposed New Ovarian Cancer Predisposing Gene
…Using data from 171 CARTaGENE participants and other sources, they confirmed that a specific FANCI variant is associated with ovarian cancer and discovered potential genetic links to other cancer types….
Psychosocial factors, health behaviors and risk of cancer incidence: Testing interaction and effect modification in an individual participant data meta-analysis
Researchers determined whether psychosocial factors interact with or modify the effects of health behaviors, such as smoking and alcohol use, in relation to cancer incidence. Data were used from 22…
Quantifying the Predictive Accuracy of a Polygenic Risk Score for Predicting Incident Cancer Cases: Application to the CARTaGENE Cohort
This study evaluated the 5-year predictivity of an 18-single nucleotide polymorphism PRS for incident breast cancer cases in the CARTaGENE cohort using pseudo R^2 indices. It concluded that the proposed…