Search results Showing 10 of 10 results for “cancer du sein”
The Genetic and Molecular Analyses of RAD51C and RAD51D Identifies Rare Variants Implicated in Hereditary Ovarian Cancer from a Genetically Unique Population
This study aimed to identify specific genetic mutations associated with increased risk of ovarian cancer. The mutations they discovered were found in many early-onset cases, particularly RAD51D, suggesting their role…
Investigating the causal role of MRE11A p.E506* in breast and ovarian cancer
This study investigated if MRE11A is a true predisposition gene for hereditary breast and ovarian cancer. Investigations suggested that the identified variant is not associated with an increased risk of…
Validation of breast cancer risk assessment tools on a French-Canadian population-based cohort
This study evaluated the use of the Breast Cancer Risk Assessment Tool (BCRAT), International Breast Cancer Intervention Study risk evaluation tool (IBIS), Polygenic Risk Scores (PRS) and combined scores to…
Dietary patterns with combined and site-specific cancer incidence in Alberta’s Tomorrow Project cohort
This study used data from the Alberta’s Tomorrow Project to examine the association between dietary patterns derived with two methods, and combined and site-specific cancer incidence in Canada….
Five-year absolute risk estimates of colorectal cancer based on CCRAT model and polygenic risk scores: A validation study using the Quebec population-based cohort CARTaGENE
This study aimed to assess the Colorectal Cancer Risk Assessment tool’s predictive performance alongside three polygenic risk scores to predict the occurrence of colorectal cancer within five years. Using data…
Stage shifting by modifying the determinants of breast cancer stage at diagnosis: a simulation study
The researchers sought to understand how lifestyle factors influence the stage at which breast cancer is diagnosed. Using data from 492 participants in Alberta’s Tomorrow Project, they found that increasing…
Arsenic Speciation and Metallomics Profiling of Human Toenails as a Biomarker to Assess Prostate Cancer Cases: Atlantic PATH Cohort Study
…between prostate cancer cases and controls, and evaluate the utility of toenail and urine biomarkers. Toenails were found to be viable biomarkers for altered arsenic speciation in prostate cancer cases….
Investigating the oral microbiome in retrospective and prospective cases of prostate, colon, and breast cancer
Salivary samples from the Atlantic Partnership for Tomorrow’s Health (PATH) project and Alberta’s Tomorrow Project (ATP) to examine the existence of prostate, colon, and breast cancer biomarkers in the human…
Toenail arsenic species and metallome profiles associated with breast, cervical, prostate, and skin cancer prevalence in the Atlantic Partnership for Tomorrow’s Health cohort
…characterize the profiles of arsenic species and metallome in the toenails of four cancer groups, compare them to healthy participants, and assess potential associations between the profiles with cancer prevalence….
Development and external validation of partial proportional odds risk prediction models for cancer stage at diagnosis among males and females in Canada
This study examined health patterns in Alberta’s Tomorrow Project participants before cancer diagnosis to find factors related to cancers caught early versus late. The researchers found factors then tested them…