Search results Showing 10 of 10 results for “breast cancer”
Personalized Risk Assessment for Prevention and Early Detection of Breast Cancer: Generating Canadian Risk Estimates
Breast cancer is the most common cancer and second leading cause of cancer death in Canadian women. A woman faces a one in eight chance of developing the disease in…
The genetic epidemiology of breast cancer: CanPath Application to the Confluence Project
Genome wide association studies (GWAS) have been successful in identifying over 180 common susceptibility loci (specific physical locations of a gene on a chromosome) for breast cancer. However, heritability analyses…
Cancer early detection and classification using methylome analysis of cell-free DNA
…cancer). We will identify cfDNA fragments that are uniquely methylated in pre-cancer blood to develop cancer-specific cfDNA markers. Our investigation using pre-cancer plasma from the Ontario Health Study revealed signatures…
Quantifying the Cancer Incidence Burden due to Lifestyle and Environment in Canada - The Canadian Population Attributable Risk of Cancer Project (ComPARe)
Despite well-established associations between modifiable lifestyle and environmental risk factors and cancer risk, reductions in these risk exposures have not produced declines in cancer incidence in Canada. This lack of…
Investigating the Roles of Radon Exposure, Air Pollution, and Diet on Lung Cancer Risk in the Canadian Partnership for Tomorrow Project
Lung cancer is the most common cancer among Canadians, accounting for 14% of all new cases and 26% of all deaths. The lung cancer five-year survival rate is among the…
Improving Lung Cancer Risk Prediction & Application
Lung cancer is the leading cause of cancer death in Canada and the World. Lung screening with computed tomography (CT) can identify lung cancers early, when they are still treatable,…
Primary Prevention of Cancer-Causing Substance Use in Gender Minority People of Canada
About 50% of cancer diagnoses are preventable by adopting healthy lifestyle behaviours such as limiting the consumption of alcohol and tobacco. World-renowned cancer research organizations have reported that there is…
Provincial Variation in Cancer Screening Uptake Across Canada: A Descriptive Overview
Population screening has been found to decrease the mortality and morbidity of cancer. Currently, cancer screening guidelines for breast, cervical, and colorectal cancer have been implemented or are in the…
Epidemiological risk model to inform targeted prevention strategies in endometrial cancer
…gender variations and environmental exposures, may also contribute to endometrial cancer risk. Other health conditions are known to contribute to endometrial cancer, but their causal relationships have not been fully…
Substance use among men and women across Canada – implications for primary prevention of cancer
…conditions, including cancer and heart disease. While research on cannabis and e-cigarette use and health is limited, largely due to their novel legal status in Canada, use of these substances…