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Rheumatoid arthritis-relevant DNA methylation changes identified in ACPA-positive asymptomatic individuals using methylome capture sequencing
…is a key marker for rheumatoid arthritis. They measured the DNA methylation of 137 subjects, 63 who were ACPA-positive, 66 were negative and 8 were self-reported with their rheumatoid arthritis….
Care quality for rheumatoid arthritis patients in Quebec
The main objectives of this study were to determine the number of CARTaGENE participants with rheumatoid arthritis that fulfilled pre-specified quality indicators and to examine the variation in DMARD use…
Identifying Rheumatoid Arthritis Cases within the Quebec Health Administrative Database
The team’s objective was to calculate rheumatoid arthritis point prevalence in the CARTaGENE cohort. They also aimed to estimate sensitivity/specificity. In the study, they were looking at 3 factors: number…
Understanding the connections between air pollution and rheumatic disease
…inflammation. Drawing on her extensive work with CanPath, Dr. Bernatsky has demonstrated potential associations between air pollutants, including PM2.5, and autoimmunity and rheumatic diseases. In this session, Dr. Bernatsky will…
Frequently Asked Questions
…CanPath data being used for any projects related to arthritis? Arthritis is one of the most common conditions among participants. Find publications about arthritis using CanPath data at this link….
Webinar: The Canadian Network for Advanced Interdisciplinary Methods (CAN-AIM) in Comparative Effectiveness Research
…many peer-reviewed papers on drug safety and effectiveness projects in many disease areas. Dr. Sasha Bernatsky Sasha Bernatsky, MD, PhD, FRCPC Dr. Bernatsky is a James McGill Professor of Medicine…
Adiposity Measures and Plasma Adipokines in Females with Rheumatoid and Osteoarthritis
…8.2 μg/ml, leptin levels were 10.3, 13.7, and 11.5 ng/ml, and resistin levels were 10.0, 12.1, and 10.8 ng/ml in participants without arthritis, with rheumatoid arthritis, and with osteoarthritis, respectively….
Long-term exposure to a mixture of industrial SO 2, NO 2, and PM 2.5 and anti-citrullinated protein antibody positivity
The research team looked at exposures to SO2, NO2, and fine particles matter on anti-citrullinated protein antibodies, a characteristic biomarker for rheumatoid arthritis (RA). It was found that there was…
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