Search results Showing 10 of 10 results for “breast cancer”
Uncovering the Contribution of Moderate-Penetrance Susceptibility Genes to Breast Cancer by Whole-Exome Sequencing and Targeted Enrichment Sequencing of Candidate Genes in Women of European Ancestry
The aim of this study was to perform a large-scale whole-exome sequencing study, followed by a targeted validation, in breast cancer patients and healthy women of European descent. Using data…
G1 Gene-environment-lifestyle factors in breast cancer susceptibility: machine learning tools to build predictive models
…predictive models for personalized breast screening. They were able to develop good predictive models for etiologies that would cause disease, and hope their model will aid in preventing breast cancer….
A two-stage association study identifies methyl-CpG-binding domain protein 2 gene polymorphisms as candidates for breast cancer susceptibility
…a genome-wide study. They restricted their analysis to DNA polymorphisms and selected 22 SNPS. There were certain SNPs that were found to be relevant to breast cancer susceptibility in populations….
Investigating the oral microbiome in retrospective and prospective cases of prostate, colon, and breast cancer
Salivary samples from the Atlantic Partnership for Tomorrow’s Health (PATH) project and Alberta’s Tomorrow Project (ATP) to examine the existence of prostate, colon, and breast cancer biomarkers in the human…
Stage shifting by modifying the determinants of breast cancer stage at diagnosis: a simulation study
The researchers sought to understand how lifestyle factors influence the stage at which breast cancer is diagnosed. Using data from 492 participants in Alberta’s Tomorrow Project, they found that increasing…
Inherited Chromosomally Integrated Human Herpesvirus 6 and Breast Cancer
…they wanted to do know if such a mutation predisposes a person to cancer development. They found there was no statistically significant association between HHV-6 and breast cancer in women….
Personalized breast cancer onset prediction from lifestyle and health history information
This article proposes a method for predicting when a woman will develop breast cancer (Bca) based on health and lifestyle history using data from 18,288 women in Alberta’s Tomorrow Project….
The association between religiosity, spirituality, and breast cancer screening: A cross-sectional analysis of Alberta's Tomorrow Project
Researchers explored data from 2,569 ATP participants regarding religiosity, spirituality, and breast cancer screening. They found that greater religiosity and spirituality salience were unrelated to mammogram receipt. However, they suggest…
Identification of a Breast Cancer Susceptibility Locus at 4q31.22 Using a Genome-Wide Association Study Paradigm
…prognostic variants across studies. All SNP associations reported with breast cancer were also adjusted for body mass index (BMI). We report a strong association with 4q31.22-rs1429142 (combined per allele odds…
Exome Sequencing in BRCA1- and BRCA2-Negative Greek Families Identifies MDM1 and NBEAL1 as Candidate Risk Genes for Hereditary Breast Cancer.
This study used CARTaGENE control data to find there relationship between the BRAC1-2 genes and breast cancer…