Search results Showing 10 of 10 results for “breast cancer”

Founder BRCA1/BRCA2/PALB2 pathogenic variants in French-Canadian breast cancer cases and controls

The purpose of this study was to evaluate the efficacy of genetic testing for these variants of the BRCA gene in Montreal French Canadians. A total of 555 breast cancer

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Uncovering the Contribution of Moderate-Penetrance Susceptibility Genes to Breast Cancer by Whole-Exome Sequencing and Targeted Enrichment Sequencing of Candidate Genes in Women of European Ancestry

The aim of this study was to perform a large-scale whole-exome sequencing study, followed by a targeted validation, in breast cancer patients and healthy women of European descent. Using data…

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G1 Gene-environment-lifestyle factors in breast cancer susceptibility: machine learning tools to build predictive models

…predictive models for personalized breast screening. They were able to develop good predictive models for etiologies that would cause disease, and hope their model will aid in preventing breast cancer….

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A two-stage association study identifies methyl-CpG-binding domain protein 2 gene polymorphisms as candidates for breast cancer susceptibility

…a genome-wide study. They restricted their analysis to DNA polymorphisms and selected 22 SNPS. There were certain SNPs that were found to be relevant to breast cancer susceptibility in populations….

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Investigating the oral microbiome in retrospective and prospective cases of prostate, colon, and breast cancer

Salivary samples from the Atlantic Partnership for Tomorrow’s Health (PATH) project and Alberta’s Tomorrow Project (ATP) to examine the existence of prostate, colon, and breast cancer biomarkers in the human…

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Stage shifting by modifying the determinants of breast cancer stage at diagnosis: a simulation study

The researchers sought to understand how lifestyle factors influence the stage at which breast cancer is diagnosed. Using data from 492 participants in Alberta’s Tomorrow Project, they found that increasing…

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Inherited Chromosomally Integrated Human Herpesvirus 6 and Breast Cancer

…they wanted to do know if such a mutation predisposes a person to cancer development. They found there was no statistically significant association between HHV-6 and breast cancer in women….

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Personalized breast cancer onset prediction from lifestyle and health history information

This article proposes a method for predicting when a woman will develop breast cancer (Bca) based on health and lifestyle history using data from 18,288 women in Alberta’s Tomorrow Project….

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The association between religiosity, spirituality, and breast cancer screening: A cross-sectional analysis of Alberta's Tomorrow Project

Researchers explored data from 2,569 ATP participants regarding religiosity, spirituality, and breast cancer screening. They found that greater religiosity and spirituality salience were unrelated to mammogram receipt. However, they suggest…

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Association between nitrogen dioxide and incident breast cancer in Alberta’s tomorrow project

…of breast cancer. Hazard ratios for every 10 ppb rise in NO₂ were from 1.01 to 1.10, indicating no discernible correlation. The results are consistent with data from throughout the…

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